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Echinoderm Microtubule-Associated Protein-Like 4

Known as: EMAP-4, Restrictedly Overexpressed Proliferation-Associated Protein, EML4 
Echinoderm microtubule-associated protein like 4 (981 aa, ~109 kDa) is encoded by the human EML4 gene. This protein may play a role in the… 
National Institutes of Health

Related topics

Related topics

8 relations
Cell MovementCytokinesisCytoskeletal GeneCytoskeleton

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Successful rechallenge with ceritinib after leukocytoclastic vasculitis during ceritinib treatment for non-small cell lung cancer harboring the EML4-ALK fusion protein
Anaplastic lymphoma kinase (ALK)-tyrosine kinase inhibitors (TKIs) dramatically improve progression-free survival compared to… 
2015
2015
Neoadjuvant Crizotinib Administration and Surgical Resection of Lung Cancer Associated with EML4/ALK Gene Translocation
━━ Background. Advances in research of the genes responsible for non-small cell lung cancer, especially adenocarcinoma, have now… 
2015
2015
EML4 –ALK 融合型がん遺伝子
EML4 –ALK 遺伝子は，2007年に非小細胞肺がんにおいて発見された新たながん遺伝子で，受容体型チロシンキナーゼをコードしており，遺伝子融合によって恒常的にチロシンキナーゼ活性が亢進する結果，がん化に寄与する．本遺伝子陽性肺がんに対してはALK… 
Review
2012
Review
2012
Promoting Equity for Women Administrators of Color Presenters:
The purpose of this study was to conduct trend and predictive analyses using both the National Center for Education Statistics… 
2011
2011
[What choice of first-line treatment?].
2011
2011
Abstract 3574: Identification and preclinical characterization of CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase, in lymphoma and non-small cell lung…
Anaplastic lymphoma kinase (ALK) was originally identified as the oncogenic NPM (nucleophosmin)-ALK fusion protein due to a t (2… 
Review
2010
Review
2010
Anaplastic lymphoma kinase as a therapeutic target in anaplastic large cell lymphoma, non-small cell lung cancer and neuroblastoma.
Anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase in the insulin receptor superfamily, was originally identified as… 
2010
2010
Expression analysis of EML4 in normal lung tissue and non-small cell lung cancer (NSCLC) in the absence and presence of chemotherapeutics.
Despite considerable progress in the development of individualized targeted therapies of tumor diseases, identification of… 
2009
2009
Dosage fish pour détecter la fusion entre eml4 et alk dans le cancer du poumon
L’invention se rapporte a des procedes et a des compositions destinees a realiser un dosage FISH pour detecter une inversion… 
2000
2000
Cloning and localization of C2orf2(ropp120), a previously unknown WD repeat protein.
Ropp 120 (restrictedly overexpressed proliferation-associated protein) is a cytoplasmic protein of 120 kDa that is significantly… 
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