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Echinoderm Microtubule-Associated Protein-Like 4

Known as: EMAP-4, Restrictedly Overexpressed Proliferation-Associated Protein, EML4 
Echinoderm microtubule-associated protein like 4 (981 aa, ~109 kDa) is encoded by the human EML4 gene. This protein may play a role in the… 
National Institutes of Health

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Cell MovementCytokinesisCytoskeletal GeneCytoskeleton

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Neoadjuvant Crizotinib Administration and Surgical Resection of Lung Cancer Associated with EML4/ALK Gene Translocation
━━ Background. Advances in research of the genes responsible for non-small cell lung cancer, especially adenocarcinoma, have now… 
2015
2015
EML4 –ALK 融合型がん遺伝子
EML4 –ALK 遺伝子は，2007年に非小細胞肺がんにおいて発見された新たながん遺伝子で，受容体型チロシンキナーゼをコードしており，遺伝子融合によって恒常的にチロシンキナーゼ活性が亢進する結果，がん化に寄与する．本遺伝子陽性肺がんに対してはALK… 
2015
2015
Nivolumab for advanced squamous cell lung cancer: what are the next steps?
2013
2013
EML4-ALK mutation in Austrian patients with NSCLC: A multicenter study.
e19093 Background: EML4 (echinoderm microtubule-associated protein-like 4) - ALK (anaplastic lymphoma kinase) fusion-type… 
2011
2011
[What choice of first-line treatment?].
2011
2011
Quel choix de traitement en première ligne
2011
2011
Abstract 3574: Identification and preclinical characterization of CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase, in lymphoma and non-small cell lung…
Anaplastic lymphoma kinase (ALK) was originally identified as the oncogenic NPM (nucleophosmin)-ALK fusion protein due to a t (2… 
2011
2011
Utility of cytopathology in diagnosis and molecular testing of lung cancer
We read with interest the editorial by Booton et al 1 on advances in the treatment and diagnosis of non-small cell lung cancer… 
2009
2009
Dosage fish pour détecter la fusion entre eml4 et alk dans le cancer du poumon
L’invention se rapporte a des procedes et a des compositions destinees a realiser un dosage FISH pour detecter une inversion… 
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