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EXTL3 protein, human

Known as: Hereditary Multiple Exostoses Gene Isolog, exostoses (multiple)-like 3 protein, human, EXTL3 
Exostosin-like 3 (919, ~105 kDa) is encoded by the human EXTL3 gene. This protein is involved in protein glycosylation and the unfolded protein… Expand
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
Transcellular propagation of protein aggregate “seeds” has been proposed to mediate the progression of neurodegenerative diseases… Expand
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2017
2017
We studied three patients with severe skeletal dysplasia, T cell immunodeficiency, and developmental delay. Whole-exome… Expand
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2017
2017
EXTL3 regulates the biosynthesis of heparan sulfate (HS), important for both skeletal development and hematopoiesis, through the… Expand
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2014
2014
Background: The function and biosynthetic mechanism of GlcNH3+ in heparan sulfate remain unclear. Results: GlcNH3+-containing… Expand
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Highly Cited
2012
Highly Cited
2012
Epithelial keratinocyte proliferation is an essential element of wound repair, and abnormal epithelial proliferation is an… Expand
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2010
2010
Neurological pathology is characteristic of the mucopolysaccharidoses (MPSs) that store heparan sulphate (HS) glycosaminoglycan… Expand
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2008
2008
Exostoses like‐3 (EXTL3) is a putative tumour suppressor gene but its involvement in colorectal cancer (CRC) is unclear. We have… Expand
Highly Cited
2007
Highly Cited
2007
The exostosin (EXT) family of genes encodes glycosyltransferases involved in heparan sulfate biosynthesis. Five human members of… Expand
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Highly Cited
2004
Highly Cited
2004
Retinal ganglion cell (RGC) axons are topographically ordered in the optic tract according to their retinal origin. In zebrafish… Expand
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Highly Cited
2001
Highly Cited
2001
The tumor suppressors EXT1 and EXT2 are associated with hereditary multiple exostoses and encode bifunctional… Expand
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