EXTL2 gene

Known as: EXTL2, Exostoses (Multiple)-Like 2 Gene, MULTIPLE EXOSTOSES-LIKE 2 
This gene is involved in the biosynthesis of heparin/heparin sulfate and carbohydrate metabolism.
National Institutes of Health

Papers overview

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2015
2015
Heparan sulfate proteoglycans are ubiquitously located on cell surfaces and in the extracellular matrices. The negatively charged… Expand
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Review
2014
Review
2014
The gene products of two members of the EXT gene family, EXT1 and EXT2, function together as a polymerase in the biosynthesis of… Expand
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2013
2013
Mutant alleles of EXT1 or EXT2, two members of the EXT gene family, are causative agents in hereditary multiple exostoses, and… Expand
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2013
2013
The gene products of two members of the EXT (exostosin) gene family, EXT1 and EXT2, function together as a polymerase in the… Expand
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2010
2010
Neurological pathology is characteristic of the mucopolysaccharidoses (MPSs) that store heparan sulphate (HS) glycosaminoglycan… Expand
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2010
2010
HS (heparan sulfate) is synthesized by HS co-polymerases encoded by the EXT1 and EXT2 genes (exostosin 1 and 2), which are known… Expand
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Highly Cited
2007
Highly Cited
2007
The exostosin (EXT) family of genes encodes glycosyltransferases involved in heparan sulfate biosynthesis. Five human members of… Expand
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2000
2000
Human EXTL2 is an alpha1,4-N-acetylhexosaminyltransferase involved in the biosynthesis of heparin/heparan sulfate. We have cloned… Expand
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1999
1999
Hereditary multiple exostoses (EXT; MIM 133700) is an autosomal dominant bone disorder. It is genetically heterogeneous with at… Expand
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1997
1997
Recently, two homologous genes, EXT1 and EXT2, with a putative tumor suppressor function have been described. Mutations in both… Expand
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