EXTL2 gene

Known as: EXTL2, Exostoses (Multiple)-Like 2 Gene, MULTIPLE EXOSTOSES-LIKE 2 
This gene is involved in the biosynthesis of heparin/heparin sulfate and carbohydrate metabolism.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
02419972017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Sanfilippo syndrome is a rare lysosomal storage disorder caused by an impaired degradation of heparan sulfate (HS). It presents… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2013
2013
Mutant alleles of EXT1 or EXT2, two members of the EXT gene family, are causative agents in hereditary multiple exostoses, and… (More)
Is this relevant?
2010
2010
Neurological pathology is characteristic of the mucopolysaccharidoses (MPSs) that store heparan sulphate (HS) glycosaminoglycan… (More)
  • table 1
  • figure 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
The exostosin (EXT) family of genes encodes glycosyltransferases involved in heparan sulfate biosynthesis. Five human members of… (More)
Is this relevant?
2006
2006
Glycosyltransferases encompass one of the largest families of enzymes found in nature. Their principle function is to catalyze… (More)
Is this relevant?
2003
2003
EXTL2, an alpha1,4-N-acetylhexosaminyltransferase, catalyzes the transfer reaction of N-acetylglucosamine and N… (More)
  • figure 1
  • figure 2
  • table II
  • figure 3
  • figure 4
Is this relevant?
2001
2001
The proteins encoded by the EXT1, EXT2, and EXTL2 genes, members of the hereditary multiple exostoses gene family of tumor… (More)
Is this relevant?
2000
2000
Human EXTL2 is an alpha1,4-N-acetylhexosaminyltransferase involved in the biosynthesis of heparin/heparan sulfate. We have cloned… (More)
Is this relevant?
1999
1999
We previously demonstrated a unique alpha-N-acetylgalactosaminyltransferase that transferred N-acetylgalactosamine (GalNAc) to… (More)
Is this relevant?
1998
1998
Hereditary multiple exostoses (EXT) is an autosomal dominant disorder that is characterized by the appearance of multiple… (More)
Is this relevant?