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EXT1 protein

Known as: EC 2.4.1.225, Glucuronosyl-N-Acetylglucosaminyl-Proteoglycan/N-Acetylglucosaminyl-Proteoglycan 4-Alpha-N-Acetylglucosaminyltransferase, heparan sulfate copolymerase EXT1 
Exostosin-1 (746 aa, ~86 kDa) is encoded by the human EXT1 gene. This protein is involved in the biosynthesis of glycosaminoglycans, bone formation… 
National Institutes of Health

Related topics

Related topics

15 relations
Carbohydrate MetabolismEXT1 geneEndoplasmic ReticulumEnzyme Gene

Broader (1)

N-Acetylglucosaminyltransferases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Severe equinovarus deformity correction using six-axis Ortho-SUV external fixator and arthroscopic-assisted ankle arthrodesis: A case report
INTRODUCTION Equinus is defined as the inability of the ankle to perform dorsiflextion for normal gait which leads to lower limb… 
2016
2016
Dual hydrogen-bonding motifs in complexes formed between tropolone and formic acid.
The near-ultraviolet π*←π absorption system of weakly bound complexes formed between tropolone (TrOH) and formic acid (FA) under… 
Review
2015
Review
2015
Mutational Analysis of Exostosin 1 and 2 Genes in Multiple Osteochondroma
To the Editor: Multiple Osteochondroma (MO) or Multiple Exostosis is a skeletal disorder characterized by out-growth of benign… 
2014
2014
Transendothelial migration of effector T cells across inflamed endothelial barriers does not require heparan sulfate proteoglycans.
Leukocyte diapedesis is a chemotactic multistep process that requires optimal chemoattractant presentation by the endothelial… 
2014
2014
Granulin-epithelin precursor interacts with heparan sulfate on liver cancer cells
Summary The first study to demonstrate HS to affect GEP binding on the cell surface. 
2014
2014
Zygotic expression of Exostosin1 (Ext1) is required for BMP signaling and establishment of dorsal-ventral pattern in Xenopus.
Exostosin 1 (EXT1) is a glycosyltransferase that contributes to the biosynthesis of heparan sulfate proteoglycans (HSPG). Loss of… 
2014
2014
Identification of a novel EXT1 mutation in patients with hereditary multiple exostosis by exome sequencing
Hereditary multiple exostosis (HME) is an autosomal inherited skeletal disease whose etiology is not fully understood. To further… 
2002
2002
Comparison of extenders, dilution ratios and theophylline addition on the function of cryopreserved walleye semen.
1997
1997
The murine Ext1 gene shows a high level of sequence similarity with its human homologue and is part of a conserved linkage group on chromosome 15.
We have cloned and sequenced the murine homologue of the human EXT1 gene. At the protein level, these genes show almost complete… 
1987
1987
Reactive subpontine exostoses.
  • N. SavageW. Young
  • Oral surgery, oral medicine, and oral pathology
  • 1987
  • Corpus ID: 13253608
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