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EXP-3179
Known as:
EXP 3179
, EXP3179
National Institutes of Health
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Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Structural basis for platelet antiaggregation by angiotensin II type 1 receptor antagonist losartan (DuP-753) via glycoprotein VI.
K. Ono
,
H. Ueda
,
+4 authors
H. Takahashi
Journal of Medicinal Chemistry
2010
Corpus ID: 36033876
GPVI is a key receptor for collagen-induced platelet activation. Loss or inhibition of GPVI causes only mildly prolonged bleeding…
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2009
2009
Losartan Metabolite EXP 3179 An AT 1-Receptor – Independent Treatment Strategy for Patients With the Metabolic Syndrome ?
G. Rossi
2009
Corpus ID: 19371305
Losartan potassium, the first orally active nonpeptide angiotensin receptor blocker (ARB) to be introduced for clinical use in…
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2009
2009
Protein kinase C-inhibiting properties of the losartan metabolite EXP3179 make the difference.
P. Wenzel
,
Eberhard Schulz
,
T. Münzel
HYPERTENSION
2009
Corpus ID: 29746051
The inhibition of the renin-angiotensin axis with the angiotensin II (ATII) receptor blockers, such as losartan, candesartan, and…
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2009
2009
Protein Kinase C – Inhibiting Properties of the Losartan Metabolite EXP 3179 Make the Difference
P. Wenzel
,
Eberhard Schulz
,
T. Münzel
2009
Corpus ID: 6598786
The inhibition of the renin-angiotensin axis with the angiotensin II (ATII) receptor blockers, such as losartan, candesartan, and…
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2008
2008
Abstract 2468: Chronic Treatment Of Hypertensive Patients With The At1 Receptor Blocker Losartan Results In Sufficient Serum Levels Of The Metabolite Exp3179 Exhibiting Ppar{gamma}-stimulating…
K. Kappert
,
O. Tsuprykov
,
+9 authors
U. Kintscher
2008
Corpus ID: 67883040
2007
2007
EXP3179 Inhibits Collagen-Dependent Platelet Activation via Glycoprotein Receptor-VI Independent of AT1-Receptor Antagonism: Potential Impact on Atherothrombosis
C. Grothusen
,
S. Umbreen
,
+9 authors
M. Gawaz
Arteriosclerosis, Thrombosis and Vascular Biology
2007
Corpus ID: 2080830
Objective—Thrombus formation after atherosclerotic plaque rupture critically involves the platelet collagen receptor glycoprotein…
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2000
2000
Losartan inhibits cyclooxygenase-2-dependent generation of pro-inflammatory and pro-aggregatory prostaglandins via its EXP3179 metabolite
J. Sunkomat
,
C. Kraemer
,
+7 authors
B. Schieffer
2000
Corpus ID: 91956907
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