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A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
OBJECTIVES We prospectively investigated the prevalence of curable forms of primary aldosteronism (PA) in newly diagnosed hypertensive patients. BACKGROUND The prevalence of curable forms of PA isExpand
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Endothelial function and dysfunction. Part I: Methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the
An enormous number of studies in the last two decades have been devoted to investigating the role of the endothelium in cardiovascular diseases. Nonetheless, the optimal methodology for investigatingExpand
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Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European
Dysfunction of the vascular endothelium is a hallmark of most conditions that are associated with atherosclerosis and is therefore held to be an early feature in atherogenesis. However, theExpand
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An Expert Consensus Statement on Use of Adrenal Vein Sampling for the Subtyping of Primary Aldosteronism
Adrenal venous sampling is recommended by current guidelines to identify surgically curable causes of hyperaldosteronism but remains markedly underused. Key factors contributing to the poor use ofExpand
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Residual electron density at theM2 site inC2/c clinopyroxenes: Relationships with bulk chemistry and sub-solidus evolution
The systematic study of both natural and synthetic clinopyroxenes often indicates the presence in the difference Fourier map of a maximum of residual density of up to 0.8 electrons, here labelledM2′,Expand
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Morphological response to positive end expiratory pressure in acute respiratory failure. Computerized tomography study
SummaryTen patients with acute respiratory failure (ARF), (4 pneumonia, 4 sepsis, 2 polytrauma), underwent computerized tomography (CT) of the lungs, (apex, hilum, base), at 5, 10, 15 cm H2O positiveExpand
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The Role of Oxidized Low-Density Lipoproteins in Atherosclerosis: The Myths and the Facts
The oxidative modification hypothesis of atherosclerosis, which assigns to oxidized low-density lipoproteins (LDLs) a crucial role in atherosclerosis initiation and progression, is still debated.Expand
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Excess ldosterone Is Associated With Alterations of Myocardial Texture in Primary Aldosteronism
Hyperaldosteronism has been causally linked to myocardial interstitial fibrosis experimentally, but it remains unclear if this link also applies to humans. Thus, we investigated the effects of excessExpand
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Orexins in the Regulation of the Hypothalamic-Pituitary-Adrenal Axis
Orexin-A and orexin-B are hypothalamic peptides that act via two G protein-coupled receptors, named orexin type 1 and type 2 receptors (OX1-Rs and OX2-Rs). The most studied biological functions ofExpand
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Adrenal vein sampling for primary aldosteronism: the assessment of selectivity and lateralization of aldosterone excess baseline and after adrenocorticotropic hormone (ACTH) stimulation
Background Adrenal vein sampling is crucial for identifying the primary aldosteronism subtypes, but the cutoff values for ascertaining selectivity of catheterization and lateralization of aldosteroneExpand
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