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EWSR1/FLI1 Fusion Gene
Known as:
FLI1/EWS FUSION GENE
, EWS/FLI1 Fusion Gene
, EWSR1-FLI1 Fusion Gene
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A fusion gene that results from a chromosomal translocation t(11;22)(q24;q12) which fuses the first seven or ten exons of the EWSR1 gene with exon 5…
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National Institutes of Health
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Related topics
Related topics
17 relations
Askin's tumor
EWS-FLI1 fusion protein
Ewing Sarcoma of Bone
Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Abstract 2028: Transcriptional modules involving EWS-FLI1 and SRF in Ewing sarcoma
Anna M. Katschnig
,
M. Kauer
,
D. Aryee
,
Raphaela Schwentner
,
E. Lawlor
,
H. Kovar
2016
Corpus ID: 78325205
Ewing Sarcoma (ES) is an aggressive pediatric bone tumor with a high tendency to metastasize. The primary genetic aberration…
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2015
2015
Factor V: an active player in inflammation.
Hongmin Sun
Blood
2015
Corpus ID: 206941001
In this issue of Blood , [Liang et al][1] identify a critical role of coagulation factor V in host inflammation response to…
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2015
2015
The Influence of FLI1 Expression Levels on Megakaryopoiesis: Studies Using iPSCs
Karen K. Vo
,
D. Jarocha
,
R. Lyde
,
S. Sullivan
,
D. French
,
M. Poncz
2015
Corpus ID: 208434090
Jacobsen syndrome is a rare, inherited hemizygous deletion of chromosome 11q that is often associated with a dysmegakaryopoiesis…
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2015
2015
Abstract 479: Inhibition of the splicing of the EWS-FLI1 fusion transcript reverses EWS-FLI1 driven oncogenic expression in Ewing sarcoma
P. Grohar
,
Suntae Kim
,
+11 authors
N. Caplen
2015
Corpus ID: 74197744
Ewing sarcoma (ES) is a highly aggressive cancer of the bone and soft tissue. In ∼85% of ES tumors the primary oncogenic event is…
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2014
2014
Abstract LB-197: YK-4-279 is effective in treating EWS-FLI1 induced myeloid/erythroid leukemia in a transgenic mouse model
T. Minas
,
Jenny J. Han
,
Sung-hyeok Hong
,
J. Toretsky
,
A. Üren
2014
Corpus ID: 58816287
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Ewing sarcoma is an aggressive neoplasm affecting bone and…
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2008
2008
Neural differentiation arrest in embryonal carcinoma cells with forced expression of EWS-FLI1
Yu Yang
,
Lanjing Zhang
,
+5 authors
Jie Zheng
Journal of Neuro-Oncology
2008
Corpus ID: 22526513
Ewing’s sarcoma/primitive neuroectodermal tumor (EWS/PNET) has a characteristic chimeric oncogene EWS-FLI1, which results from…
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2007
2007
EWS-FLI1 interferes with p53-dependent growth control in Ewing´s sarcoma by suppressing autostimulation of the NOTCH pathway
J. Ban
,
K. Schaefer
,
M. Kreppel
,
R. Bachmaier
,
H. Kovar
2007
Corpus ID: 204055908
2109 The EWS-FLI1 fusion oncoprotein is the driving force in the pathogenesis of Ewing´s sarcoma family tumors (ESFT). It acts as…
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Review
2003
Review
2003
Potentials for RNAi in sarcoma research and therapy: Ewing's sarcoma as a model.
H. Kovar
,
J. Ban
,
Š. Pospíšilová
Seminars in Cancer Biology
2003
Corpus ID: 8628845
2003
2003
Diagnostic significance and clinical applications of chimeric genes in Ewing's sarcoma.
N. Yoshino
,
T. Kojima
,
+9 authors
Takashi Suzuki
Biological and Pharmaceutical Bulletin
2003
Corpus ID: 26007373
Ewing's sarcoma (ES) is one of the most malignant bone and soft tissue tumors in childhood. Morphologically, ES belongs to the…
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