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Background: 2-Methoxyestradiol (2ME2) is an endogenous metabolite of 17-β-estradiol with anti-proliferative and anti-angiogenic… Expand 2-methoxyestradiol (2ME) is an endogenous 17β-oestradiol metabolite that exerts antiproliferative, antiangiogenic and antitumour… Expand Abstract Angiogenesis is a closely controlled biological process that takes place during fetal development of blood vessels and… Expand Cancer is the second leading cause of death in South Africa. The critical role that microtubules play in cell division makes them… Expand Background2-Ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16) is a unique, in silico-designed compound with possible… Expand Background2-Methoxyestradiol is known to have antitumour and antiproliferative action in vitro and in vivo. However, when 2… Expand Effects of estradiol analogues on blood : a pilot study
This study demonstrated that both ESE-15-ol en ESE-16 have no effect on… Expand The aim of this study was to characterize the in vitro action of 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16) on… Expand Background2-Methoxyestradiol has been shown to induce both autophagy and apoptosis in various carcinogenic cell lines. Although a… Expand