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ERRFI1 wt Allele

Known as: Mitogen-Inducible Gene 6, Receptor-Associated Late Transducer Gene, RALT 
Human ERRFI1 wild-type allele is located in the vicinity of 1p36 and is approximately 22 kb in length. This allele, which encodes ERBB receptor… Expand
National Institutes of Health

Related topics

Related topics

7 relations
1p36Cellular Stress ResponseSignal TransductionSignal Transduction Inhibition
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Broader (1)

ERRFI1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma.
Great interest persists in useful prognostic and therapeutic targets in glioblastoma. In this study, we report the definition of… Expand
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Highly Cited
2010
Highly Cited
2010
Mig-6 controls EGFR trafficking and suppresses gliomagenesis.
Glioblastoma multiforme (GBM) is the most common and lethal primary brain cancer that is driven by aberrant signaling of growth… Expand
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Highly Cited
2009
Highly Cited
2009
Negative regulation of the EGFR-MAPK cascade by actin-MAL-mediated Mig6/Errfi-1 induction.
We analyzed the G-actin-regulated transcriptome by gene expression analysis using previously characterized actin-binding drugs… Expand
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Highly Cited
2008
Highly Cited
2008
Hypoxia promotes the differentiated human articular chondrocyte phenotype through SOX9-dependent and -independent pathways.
The chondrocyte is solely responsible for synthesis and maintenance of the resilient articular cartilage matrix that gives this… Expand
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Highly Cited
2007
Highly Cited
2007
Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis.
The identification of molecular differences in the endometrium of women with endometriosis is an important step toward… Expand
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Highly Cited
2007
Highly Cited
2007
Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface
Members of the epidermal growth factor receptor family (EGFR/ERBB1, ERBB2/HER2, ERBB3/HER3 and ERBB4/HER4) are key targets for… Expand
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Highly Cited
2007
Highly Cited
2007
Evidence that MIG-6 is a tumor-suppressor gene
Mitogen-inducible gene 6 (MIG-6) is located in human chromosome 1p36, a locus frequently associated with human lung cancer. MIG-6… Expand
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Highly Cited
2003
Highly Cited
2003
Feedback inhibition by RALT controls signal output by the ErbB network
The ErbB-2 interacting protein receptor-associated late transducer (RALT) was previously identified as a feedback inhibitor of… Expand
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Highly Cited
2001
Highly Cited
2001
Mig-6 Is a Negative Regulator of the Epidermal Growth Factor Receptor Signal
Abstract In contrast to signal generation and transmission, the mechanisms and molecules that negatively regulate receptor… Expand
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Review
1994
Review
1994
[Epidermal growth factor receptor].
EGFR and Lung Cancer “When I began my postdoc in Harold Varmus’ lab at Memorial Sloan Kettering Cancer Center in 2004, EGFR… Expand
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