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ERN1 wt Allele

Known as: IRE1a, IRE1P, Endoplasmic Reticulum To Nucleus Signaling 1 wt Allele 
Human ERN1 wild-type allele is located in the vicinity of 17q24.2 and is approximately 88 kb in length. This allele, which encodes serine/threonine… 
National Institutes of Health

Related topics

Related topics

9 relations
17q24.2Alzheimer's Disease Pathway KEGGHydrolysisPhosphorylation

Papers overview

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Review
2019
Review
2019
Understanding the Role of the Unfolded Protein Response Sensor IRE1 in the Biology of Antigen Presenting Cells
The unfolded protein response (UPR) is an adaptive response that maintains the fidelity of the cellular proteome in conditions… 
2017
2017
Inhibition of IRE1 results in decreased scar formation
Wound healing is characterized by the production of large amounts of protein necessary to replace lost cellular mass and… 
2016
2016
Hypoxic regulation of MYBL1, MEST, TCF3, TCF8, GTF2B, GTF2F2 and SNAI2 genes expression in U87 glioma cells upon IRE1 inhibition.
We investigated the impact of IRE1/ERN1 (inositol requiring enzyme 1/endoplasmic reticulum to nucleus signaling 1) knockdown on… 
2015
2015
EFFECT OF HYPOXIA ON THE EXPRESSION OF GENES THAT ENCODE SOME IGFBP AND CCN PROTEINS IN U87 GLIOMA CELLS DEPENDS ON IRE1 SIGNALING.
We have studied hypoxic regulation of the expression of different insulin-like growth factor binding protein genes in U87 glioma… 
2014
2014
IRE1 inhibition perturbs the unfolded protein response in a pancreatic β-cell line expressing mutant proinsulin, but does not sensitize the cells to apoptosis
BackgroundThe Akita mutation (C96Y) in the insulin gene results in early onset diabetes in both humans and mice. Expression of… 
2014
2014
Novel Bioinformatics Method for Identification of Genome-Wide Non-Canonical Spliced Regions Using RNA-Seq Data
Setting During endoplasmic reticulum (ER) stress, the endoribonuclease (RNase) Ire1α initiates removal of a 26 nt region from the… 
2012
2012
The ER in 4D: a novel stress pathway controlling endoplasmic reticulum membrane remodeling
The endoplasmic reticulum (ER) is a fundamental cellular organelle responsible for a variety of physiological processes… 
2009
2009
USP14 inhibits ER-associated degradation via interaction with IRE1alpha.
2009
2009
Climate change: Snakes tell a torrid tale
The discovery in Colombia of a giant species of fossil snake is news in itself. But a wider, more controversial inference to be… 
Highly Cited
2006
Highly Cited
2006
Tumour necrosis factor receptor 1 mediates endoplasmic reticulum stress‐induced activation of the MAP kinase JNK
Tumour necrosis factor receptor (TNFR)1 is the main receptor responsible for TNF‐induced diverse cellular events. In this study… 
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