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ERBB4 gene

Known as: ERBB4, ONCOGENE ERBB4, V-ERB-B2 AVIAN ERYTHROBLASTIC LEUKEMIA VIRAL ONCOGENE HOMOLOG 4 
This gene is involved in neuronal development and plays a role in receptor tyrosine kinase signal transduction that regulates cellular proliferation… 
National Institutes of Health

Related topics

Related topics

12 relations
AMYOTROPHIC LATERAL SCLEROSIS 19Cell Proliferation Regulatory ProcessERBB4 Receptor Protein Tyrosine KinaseHER4 Ag:PrThr:Pt:Tiss:Ord:Immune stain

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ERBB4 wt Allele

Papers overview

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2015
2015
Genetic variants in ERBB4 is associated with chronic hepatitis B virus infection
Background The role of ERBB4 in liver disease has seldom been reported. This study aims to find genetic markers at ERBB4 for… 
2013
2013
A new single gene deletion on 2q34: ERBB4 is associated with intellectual disability
We report on a 15‐year‐old patient with hyperactivity, intellectual disability and severe speech developmental delay. An array… 
2012
2012
Genetic association analysis of ERBB4 polymorphisms with the risk of schizophrenia and SPEM abnormality in a Korean population
2011
2011
Carboxyl-Group Footprinting Maps the Dimerization Interface and Phosphorylation-induced Conformational Changes of a Membrane-associated Tyrosine Kinase*
Her4 is a transmembrane receptor tyrosine kinase belonging to the ErbB-EGFR family. It plays a vital role in the cardiovascular… 
2010
2010
Molecular Cloning and Characterization of the Human ErbB4 Gene: Identification of Novel Splice Isoforms in the Developing and Adult Brain
ErbB4 is a growth factor receptor tyrosine kinase essential for neurodevelopment. Genetic variation in ErbB4 is associated with… 
Highly Cited
2009
Highly Cited
2009
Her4 and Her2/neu Tyrosine Kinase Domains Dimerize and Activate in a Reconstituted in Vitro System*
Her4 (ErbB-4) and Her2/neu (ErbB-2) are receptor-tyrosine kinases belonging to the epidermal growth factor receptor (EGFR) family… 
2009
2009
Somatic Mutations of ErbB4
Cancer drugs targeting ErbB receptors, such as epidermal growth factor receptor and ErbB2, are currently in clinical use. However… 
2005
2005
Isolation of scFvs to in vitro produced extracellular domains of EGFR family members.
The members of the epidermal growth factor receptor (EGFR) family are over expressed in a variety of malignancies and are… 
2000
2000
Morphogenetic and proliferative responses to heregulin of mammary epithelial cells in vitro are dependent on HER2 and HER3 and differ from the responses to HER2 homodimerisation or hepatocyte growth…
The effects of heregulin on the cell line HB2, derived from immortalised human luminal mammary epithelial cells, have been… 
1995
1995
HER4 Expression Correlates with Cytotoxicity Directed by a Heregulin-Toxin Fusion Protein (*)
We have constructed, expressed, and purified a fusion protein, HAR-TX β2, consisting of heregulin-β2 fused to a binding-defective… 
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