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EPHA3 gene

Known as: HUMAN EMBRYO KINASE, EPH Receptor A3 Gene, HEK4 
This gene is involved in receptor tyrosine kinase signal transduction and plays a role in lymphoid function and differentiation.
National Institutes of Health

Related topics

Related topics

11 relations
Cell Differentiation processCellular TropismEPHA3 protein, humanEPHA5 gene

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EPHA3 wt Allele

Papers overview

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2010
2010
Transient expression of an IL-23R extracellular domain Fc fusion protein in CHO vs. HEK cells results in improved plasma exposure.
2007
2007
Structural and signaling requirements of the human melanocortin 4 receptor for MAP kinase activation
2006
2006
Endothelin-1 Potentiates Capsaicin-Induced TRPV1 Currents Via the Endothelin A Receptor
Endothelin-1 (ET-1) both stimulates nociceptors and sensitizes them to painful stimuli. The cellular mechanisms of the ET-1… 
Highly Cited
2005
Highly Cited
2005
Toll‐like Receptor 2‐Mediated Gene Expression in Epithelial Cells During Helicobacter pylori Infection
Background.  Helicobacter pylori is the major pathogen causing chronic gastritis and peptic ulcer disease and is closely linked… 
Highly Cited
2005
Highly Cited
2005
Genetic Determinants of Cell Type-Specific Poliovirus Propagation in HEK 293 Cells
ABSTRACT The ability of poliovirus to propagate in neuronal cells can be reduced by introducing appropriate nucleotide… 
Highly Cited
2004
Highly Cited
2004
Sphingosine Kinase Protects Lipopolysaccharide-Activated Macrophages from Apoptosis
ABSTRACT Lipopolysaccharide (LPS) signaling is critical for the innate immune response to gram-negative bacteria. Here, evidence… 
Highly Cited
2003
Highly Cited
2003
A single viral protein HCMV US2 affects antigen presentation and intracellular iron homeostasis by degradation of classical HLA class I and HFE molecules.
HFE is a nonclassical class I molecule that associates with beta 2-microglobulin (beta 2m) and with the transferrin receptor. HFE… 
Highly Cited
1998
Highly Cited
1998
HIV-1 envelope gp120 inhibits the monocyte response to chemokines through CD4 signal-dependent chemokine receptor down-regulation.
Since HIV-1 infection results in severe immunosuppression, and the envelope protein gp120 has been reported to interact with some… 
Highly Cited
1997
Highly Cited
1997
Effects of Acute and Chronic Ethanol Exposure on Heteromeric N‐Methyl‐d‐Aspartate Receptors Expressed in HEK 293 Cells
Abstract: Ion flux through native N‐methyl‐d‐aspartate (NMDA) receptors is inhibited by behaviorally relevant concentrations of… 
Highly Cited
1965
Highly Cited
1965
STUDIES OF ADENOVIRUS SV40 HYBRID VIRUSES
E46+ virus purified by limiting dilution and plaque isolation in AGMK cells consists of a mixture of hybrid and non-hybrid virus… 
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