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EP300 gene

Known as: E1A-BINDING PROTEIN, 300-KD, KAT3B, p300 
This gene plays a role in DNA repair and regulation of transcription.
National Institutes of Health

Related topics

Related topics

5 relations
EP300 protein, humanEP400 geneTranscriptional Regulationchromatin remodeling

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EP300 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
Pharmacological inhibition of chromatin co-regulatory factors represents a clinically validated strategy to modulate oncogenic… 
Highly Cited
2016
Highly Cited
2016
Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637).
CBP and EP300 are highly homologous, bromodomain-containing transcription coactivators involved in numerous cellular pathways… 
Highly Cited
2009
Highly Cited
2009
Inhibition of Lysine Acetyltransferase KAT3B/p300 Activity by a Naturally Occurring Hydroxynaphthoquinone, Plumbagin*
Lysine acetyltransferases (KATs), p300 (KAT3B), and its close homologue CREB-binding protein (KAT3A) are probably the most widely… 
Highly Cited
2007
Highly Cited
2007
Genetic heterogeneity in Rubinstein–Taybi syndrome: delineation of the phenotype of the first patients carrying mutations in EP300
Background: Rubinstein–Taybi syndrome (RSTS) is a congenital disorder characterised by growth retardation, facial dysmorphisms… 
Highly Cited
2007
Highly Cited
2007
Confirmation of EP300 gene mutations as a rare cause of Rubinstein–Taybi syndrome
The Rubinstein–Taybi syndrome (RSTS, MIM 180849), a dominant Mendelian disorder with typical face, short stature, skeletal… 
Highly Cited
2002
Highly Cited
2002
Mutation analysis of EP300 in colon, breast and ovarian carcinomas
The putative tumour suppressor gene EP300 is located on chromosome 22q13 which is a region showing frequent loss of… 
Highly Cited
2000
Highly Cited
2000
Transcription Factor ZBP-89 Cooperates with Histone Acetyltransferase p300 during Butyrate Activation of p21 waf1 Transcription in Human Cells*
Inducible p53-independent regulation of the cyclin-dependent kinase inhibitor p21 waf1 transcription is mediated through proximal… 
Highly Cited
1996
Highly Cited
1996
Detecting simulated amnesia for autobiographical and recently learned information using the P300 event-related potential.
Highly Cited
1990
Highly Cited
1990
P300, probability, and interstimulus interval.
The relationship between target stimulus probability and interstimulus interval on the P300 (P3) component of the event-related… 
Highly Cited
1989
Highly Cited
1989
Frequency, Intensity, and Duration as Determinants of P300 from Auditory Stimuli
The auditory event-related potential was assessed in two experiments that evaluated the effects of stimulus factors on P300 (P3… 
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