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EML4 gene

Known as: ECHINODERM MICROTUBULE ASSOCIATED PROTEIN LIKE-4, Echinoderm Microtubule Associated Protein Like 4 Gene, ELP120 
A fusion gene that results from a chromosomal inversion inv(2)(p21p23) which fuses the 5' portion of the EML4 gene with exons 20-29 of the ALK gene… 
National Institutes of Health

Related topics

Related topics

36 relations
Acinar Lung AdenocarcinomaAdenocarcinoma of lung (disorder)Bronchioloalveolar AdenocarcinomaCell Movement

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EML4 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Effect of ALK-inhibitors in the treatment of non-small cell lung cancer: a systematic review and meta-analysis.
OBJECTIVE Lung cancer is the leading cause of cancer-related mortality. Over 80% of all lung cancer cases are non-small-cell lung… 
2015
2015
Nivolumab for advanced squamous cell lung cancer: what are the next steps?
2014
2014
Phase (Ph) 1/2 study of TSR-011, a potent inhibitor of ALK and TRK, including crizotinib-resistant ALK mutations.
e19005 Background: Ultimately, the majority of anaplastic lymphoma kinase (ALK) rearranged (+) non-small cell lung cancers (NSCLC… 
2014
2014
Immunohistochemistry, fluorescence in situ hybridization, and reverse transcription-polymerase chain reaction for the detection of anaplastic lymphoma kinase gene rearrangements in patients with non…
CONTEXT Echinoderm microtubule-associated protein-like 4 gene (EML4) and anaplastic lymphoma kinase gene (ALK) fusion was shown… 
2013
2013
Solitary pulmonary metastasis from lung cancer harboring EML4-ALK after a 15-year disease-free interval.
2012
2012
Effect of PF-02341066 and radiation on non-small cell lung cancer cells
Recently, a fusion protein of echinoderm microtubule associated protein like-4 (EML4) and anaplastic lymphoma kinase (ALK) has… 
2012
2012
The Author Response: EML4-ALK Fusion Gene in Korean Non-Small Cell Lung Cancer
I would like to thank the interest and comments on our paper entitled "EML4-ALK fusion gene in Korean non-small cell lung cancer… 
2011
2011
Concomitant EGFR mutation and EML4-ALK gene fusion in non-small cell lung cancer.
10517 Background: The fusion of the anaplastic lymphoma kinase (ALK) with the echinoderm microtubule-associated protein-like 4… 
2000
2000
Influenza A virus-binding activity of glycoglycerolipids of aquatic bacteria.
As the aqueous sphere has been proposed to be an important source medium for the virus infection of land animals, the glycolipids… 
2000
2000
Relationship Between p62 and p56, Two Proteins of the Mammalian Cortical Granule Envelope, and Hyalin, the Major Component of the Echinoderm Hyaline Layer, in Hamsters1
Abstract Mammalian cortical granules contain two polypeptides (p62 and p56) that are incorporated into the cortical granule… 
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