Skip to search formSkip to main contentSkip to account menu

EMD 57033

Known as: EMD-57033 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

EMD 53998

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
The Inotropic Effect of the Active Metabolite of Levosimendan, OR-1896, Is Mediated through Inhibition of PDE3 in Rat Ventricular Myocardium
Aims We recently published that the positive inotropic response (PIR) to levosimendan can be fully accounted for by… 
2005
2005
Effects of troponin C isoform on the action of the cardiotonic agent EMD 57033.
The effects of the cardiotonic potentiator EMD 57033 on different TnC (troponin C) isoforms were investigated. Endogenous… 
2002
2002
Calcium Sensitizer EMD 57033, But Not the &bgr; 1 -Adrenoreceptor Agonist Dobutamine, Increases Mechanical Efficiency in Stunned Myocardium
External work, efficiency of energy transfer (EET), and mechanical efficiency (defined as the ratio of external work over… 
2000
2000
Cardiovascular profile of the calcium sensitizer EMD 57033 in open‐chest anaesthetized pigs with regionally stunned myocardium
Ca2+ sensitizers enhance systolic function, but may impair relaxation in vitro; these effects may differ in stunned and normal… 
1997
1997
Relaxation effect of CGP-48506, EMD-57033, and dobutamine in ejecting and isovolumically beating rabbit hearts.
Because it is not known whether ejection influences the negative effect of the Ca2+-sensitizing drugs on ventricular relaxation… 
1997
1997
Relaxation effect of CGP-48506, EMD-57033, and dobutamine in ejecting and isovolumically beating rabbit hearts.
Because it is not known whether ejection influences the negative effect of the Ca(2+)-sensitizing drugs on ventricular relaxation… 
1997
1997
Cardiovascular effects of the novel Ca2+‐sensitiser EMD 57033 in pigs at rest and during treadmill exercise
1 To date no study has described the cardiovascular effects of increased myofilament Ca2+ responsiveness in awake animals both… 
1996
1996
Functional effects of EMD-57033 in isovolumically beating isolated rabbit hearts.
The results of isolated myocyte and cardiac muscle experiments indicate that inotropic agents that increase responsiveness of… 
1995
1995
EMD 57033 enhances arrhythmias associated with increased wall-stress in the working rat heart.
1. EMD 57033 produces a positive inotropic effect by increasing the sensitivity of cardiac muscle myofilaments to calcium. Since… 
1993
1993
The effect of EMD 57033, a novel cardiotonic agent, on the relaxation of skinned cardiac and skeletal muscle produced by photolysis of diazo-2, a caged calcium chelator
SummaryEMD 57033 is thought to produce its potentiating effect by increasing the apparent calcium sensitivity of myofibrils. We… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)