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ELP3 gene

Known as: ELP3, ELONGATION PROTEIN 3, S. CEREVISIAE, HOMOLOG OF, FLJ10422 
 
National Institutes of Health

Related topics

Related topics

1 relation
ELP4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Structural basis for tRNA modification by Elp3 from Dehalococcoides mccartyi
During translation elongation, decoding is based on the recognition of codons by corresponding tRNA anticodon triplets. Molecular… Expand
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2015
2015
Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine
Ladang et al. report that Elp3, a subunit of the Elongator complex, is induced by Wnt signaling and is required to initiate colon… Expand
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Highly Cited
2014
Highly Cited
2014
Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress
Glucose‐6‐phosphate dehydrogenase (G6PD) is a key enzyme in the pentose phosphate pathway (PPP) and plays an essential role in… Expand
Highly Cited
2014
Highly Cited
2014
Archaeal Elp3 catalyzes tRNA wobble uridine modification at C5 via a radical mechanism.
Approximately 25% of cytoplasmic tRNAs in eukaryotic organisms have the wobble uridine (U34) modified at C5 through a process… Expand
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Highly Cited
2010
Highly Cited
2010
A role for elongator in zygotic paternal genome demethylation
The life cycle of mammals begins when a sperm enters an egg. Immediately after fertilization, both the maternal and paternal… Expand
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2010
2010
The histone acetyltransferase Elp3 plays in active role in the control of synaptic bouton expansion and sleep in Drosophila
J. Neurochem. (2010) 115, 493–504. 
Highly Cited
2010
Highly Cited
2010
Elongator function in tRNA wobble uridine modification is conserved between yeast and plants
Based on studies in yeast and mammalian cells the Elongator complex has been implicated in functions as diverse as histone… Expand
Highly Cited
2006
Highly Cited
2006
The Elongator subunit Elp3 contains a Fe4S4 cluster and binds S‐adenosylmethionine
The Elp3 subunit of the Elongator complex is highly conserved from archaea to humans and contains a well‐characterized C‐terminal… Expand
Review
2002
Review
2002
A second catalytic domain in the Elp3 histone acetyltransferases: a candidate for histone demethylase activity?
A new subfamily of two-domain histone acetyltransferases (HATs) related to Elp3 has been identified. In addition to a HAT domain… Expand
Highly Cited
2001
Highly Cited
2001
RNA Polymerase II Elongator Holoenzyme Is Composed of Two Discrete Subcomplexes*
Elongator is a histone acetyltransferase complex that associates with the elongating form of RNA polymerase II. We purified… Expand
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