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ELAC2 wt Allele
Known as:
ElaC Ribonuclease Z 2 wt Allele
, ELC2
, HPC2
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Human ELAC2 wild-type allele is located in the vicinity of 17p11.2 and is approximately 27 kb in length. This allele, which encodes zinc…
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National Institutes of Health
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Related topics
Related topics
4 relations
17p11.2
Hydrolysis
RNA Degradation
RNA Processing
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
ELAC (3,12‐di‐O‐acetyl‐8‐O‐tigloilingol), a plant‐derived lathyrane diterpene, induces subventricular zone neural progenitor cell proliferation through PKCβ activation
Maribel Murillo‐Carretero
,
Noelia Geribaldi-Doldán
,
+11 authors
Carmen Castro
British Journal of Pharmacology
2017
Corpus ID: 207100598
Pharmacological strategies aimed to facilitate neuronal renewal in the adult brain, by promoting endogenous neurogenesis…
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2015
2015
Two Essential Light Chains Regulate the MyoA Lever Arm To Promote Toxoplasma Gliding Motility
Melanie J. Williams
,
Hernán Alonso
,
+6 authors
Christopher J. Tonkin
mBio
2015
Corpus ID: 1283343
ABSTRACT Key to the virulence of apicomplexan parasites is their ability to move through tissue and to invade and egress from…
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2010
2010
ELAC2 polymorphisms and prostate cancer risk: a meta-analysis based on 18 case–control studies
Bin Xu
,
N. Tong
,
Jun Li
,
Zhizhong Zhang
,
Han-Xin Wu
Prostate Cancer and Prostatic Diseases
2010
Corpus ID: 17272763
Polymorphisms in the elaC homolog-2 (ELAC2)/HPC2 gene have been hypothesized to alter the risk of prostate cancer. However, the…
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Highly Cited
2003
Highly Cited
2003
ELAC2/HPC2 polymorphisms, prostate-specific antigen levels, and prostate cancer.
G. Severi
,
G. Giles
,
+8 authors
J. Hopper
Journal of the National Cancer Institute
2003
Corpus ID: 18644090
BACKGROUND The ELAC2 gene has been proposed to be a prostate cancer susceptibility gene and is being referred to as HPC2, in part…
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2002
2002
Association of common missense changes in ELAC2 (HPC2) with prostate cancer in a Japanese case-control series
H. Fujiwara
,
M. Emi
,
+13 authors
S. Tavtigian
Journal of Human Genetics
2002
Corpus ID: 24180515
AbstractThe recently identified prostate cancer susceptibility gene ELAC2 (HPC2) harbors two common missense variants, a serine…
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Highly Cited
2001
Highly Cited
2001
HPC2 variants and screen-detected prostate cancer.
D. Vesprini
,
R. Nam
,
+6 authors
S. Narod
American Journal of Human Genetics
2001
Corpus ID: 42943426
Two studies have reported significant associations between susceptibility to prostate cancer and two common missense variants of…
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Highly Cited
1998
Highly Cited
1998
Characterization of Interactions between the Mammalian Polycomb-Group Proteins Enx1/EZH2 and EED Suggests the Existence of Different Mammalian Polycomb-Group Protein Complexes
R. Sewalt
,
J. van der Vlag
,
+6 authors
A. Otte
Molecular and Cellular Biology
1998
Corpus ID: 24197092
ABSTRACT In Drosophila melanogaster, thePolycomb-group (PcG) andtrithorax-group (trxG) genes have been identified as repressors…
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1998
1998
Studies of the efficacy and pharmacology of irinotecan against human colon tumor xenograft models.
William C. Zamboni
,
Clinton F. Stewart
,
+7 authors
Peter J. Houghton
Clinical Cancer Research
1998
Corpus ID: 1247165
Irinotecan, administered i.v. on days 1-5 and 8-12 [(dx5)2 i.v.] has demonstrated significant activity against advanced human…
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Review
1998
Review
1998
Hereditary prostate cancer in African-American families.
K. Cooney
Seminars in Urologic Oncology
1998
Corpus ID: 24462980
The recognition that family history is an important risk factor for the development of prostate cancer has led to the search for…
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1990
1990
Influence of dose of [6RS]leucovorin on reduced folate pools and 5-fluorouracil-mediated thymidylate synthase inhibition in human colon adenocarcinoma xenografts.
J. Houghton
,
Larry G. Williams
,
P. Cheshire
,
Irving W. Wainer
,
P. Jadaud
,
peter J. Houghton
Cancer Research
1990
Corpus ID: 21048982
Using preclinical models of human colon adenocarcinomas in immune-deprived mice, the influence of dose of [6RS]leucovorin ([6RS…
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