Skip to search formSkip to main contentSkip to account menu

EIF2B5 gene

Known as: EIF2B5, EUKARYOTIC TRANSLATION INITIATION FACTOR 2B, SUBUNIT 5, EIF2Bepsilon 
This gene plays a role in the initiation of protein biosynthesis.
National Institutes of Health

Related topics

Related topics

15 relations
Childhood Ataxia with Central Nervous System HypomyelinizationEIF2B1 geneEIF2B1 protein, humanEIF2B2 gene

Narrower (1)

EIF2B5 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Vanishing white matter disease with a novel EIF2B5 mutation: A 10-year follow-up
2017
2017
[Association between homozygous c.318A>GT mutation in exon 2 of the EIF2B5 gene and the infantile form of vanishing white matter leukoencephalopathy].
2016
2016
Use of focused exome sequencing in adult-onset leukodystrophy to identify new genes and mutations
2015
2015
Infantile onset Vanishing White Matter disease associated with a novel EIF2B5 variant, remarkably long life span, severe epilepsy, and hypopituitarism
Vanishing White Matter disease (VWM) is an inherited progressive leukoencephalopathy caused by mutations in the genes EIF2B1–5… 
2015
2015
No evidence for a role of Ile587Val polymorphism of EIF2B5 gene in multiple sclerosis in Kashmir Valley of India
2014
2014
Novel mutations identified in EIF2B5 gene in Kashmiri patients as susceptibility factor for multiple sclerosis.
White matter disease refers to a set of diseases that affect the white matter of the brain and all of which have different… 
2010
2010
Ectopic expression of eIF2Bepsilon in rat skeletal muscle rescues the sepsis-induced reduction in guanine nucleotide exchange activity and protein synthesis.
Eukaryotic initiation factor 2B (eIF2B) is a guanine nucleotide exchange factor (GEF) whose activity is both tightly regulated… 
2010
2010
Ectopic expression of eIF 2 B ε in rat skeletal muscle rescues the sepsis-induced reduction in guanine nucleotide exchange activity and protein synthesis
Tuckow AP, Vary TC, Kimball SR, Jefferson LS. Ectopic expression of eIF2Bε in rat skeletal muscle rescues the sepsis-induced… 
Highly Cited
2004
Highly Cited
2004
Structure of the Catalytic Fragment of Translation Initiation Factor 2B and Identification of a Critically Important Catalytic Residue*
Eukaryotic initiation factor (eIF) 2B catalyzes the nucleotide activation of eIF2 to its active GTP-bound state. The exchange… 
Highly Cited
2000
Highly Cited
2000
Identification of Domains and Residues within the ɛ Subunit of Eukaryotic Translation Initiation Factor 2B (eIF2Bɛ) Required for Guanine Nucleotide Exchange Reveals a Novel Activation Function…
ABSTRACT Eukaryotic translation initiation factor 2B (eIF2B) is the guanine nucleotide exchange factor for protein synthesis… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)