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EFNA2 gene

Known as: ELF-1, EPH-RELATED RECEPTOR TYROSINE KINASE LIGAND 6, EPHRIN A2 
 
National Institutes of Health

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Ephrin-A2

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Highly Cited
2002
Highly Cited
2002
Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors.
Stem cells are a central feature of metazoan biology. Haematopoietic stem cells (HSCs) represent the best-characterized example… Expand
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2002
2002
Phosphorylation and O-linked glycosylation of Elf-1 leads to its translocation to the nucleus and binding to the promoter of the TCR zeta-chain.
Elf-1, a member of the E 26-specific transcription factor family with a predicted molecular mass of 68 kDa, is involved in the… Expand
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2002
2002
Defective production of functional 98-kDa form of Elf-1 is responsible for the decreased expression of TCR zeta-chain in patients with systemic lupus erythematosus.
Systemic lupus erythematosus (SLE), the prototypic autoimmune disease, is characterized by defective expression of TCR zeta-chain… Expand
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Highly Cited
1997
Highly Cited
1997
Shared and distinct functions of RAGS and ELF-1 in guiding retinal axons.
Two ligands for Eph-related receptor tyrosine kinases, RAGS and ELF-1, have been implicated in the control of development of the… Expand
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Highly Cited
1996
Highly Cited
1996
Regulation of topographic projection in the brain: Elf-1 in the hippocamposeptal system.
The hippocampus and septum play central roles in one of the most important spheres of brain function: learning and memory… Expand
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Highly Cited
1996
Highly Cited
1996
Detection of ligands in regions anatomically connected to neurons expressing the Eph receptor Bsk: potential roles in neuron-target interaction.
Neuron-target interaction is a key feature in the establishment of neuronal networks. However, the underlying mechanism remains… Expand
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Highly Cited
1995
Highly Cited
1995
Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map
Topographic maps with a defined spatial ordering of neuronal connections are a key feature of brain organization. Such maps are… Expand
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Highly Cited
1995
Highly Cited
1995
Regulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteins.
The interleukin 2 receptor alpha-chain (IL-2R alpha) gene is rapidly and potently induced in T cells in response to mitogenic… Expand
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Highly Cited
1992
Highly Cited
1992
cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.
The recent definition of a consensus DNA binding sequence for the Ets family of transcription factors has allowed the… Expand
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Highly Cited
1991
Highly Cited
1991
Developmental function of Elf-1: an essential transcription factor during embryogenesis in Drosophila.
The Drosophila transcription factor Elf-1 binds to a cis-acting element that is essential for neuronal expression of the Dopa… Expand
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