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EC 0489

Known as: EC-0489, EC0489 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Folic AcidVinca Alkaloids
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Reducing Undesirable Hepatic Clearance of a Tumor-Targeted Vinca Alkaloid via Novel Saccharopeptidic Modifications
During a phase I trial of EC145 (a folate-targeted vinca alkaloid conjugate), constipation was identified as the dose-limiting… 
2010
2010
A phase I study of the folate-targeted conjugate EC0489 in patients with refractory or advanced metastatic cancer.
3088 Background: The folate receptor (FR) is expressed on many human tumors (e.g., ovarian, NSCLC, etc.) where it functions as a… 
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