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EAA-090
Known as:
EAA 090
, Perzinfotel
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Azabicyclo Compounds
Organophosphonates
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Effect of perzinfotel and a proprietary phospholipase A(2) inhibitor on kinetic gait and subjective lameness scores in dogs with sodium urate-induced synovitis.
S. Budsberg
,
B. Torres
,
+5 authors
S. Al-Nadaf
American Journal of Veterinary Research
2011
Corpus ID: 13126441
OBJECTIVE To investigate the ability of perzinfotel (an N-methyl-d-aspartate receptor antagonist) and a proprietary phospholipase…
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2010
2010
Effects of perzinfotel, butorphanol tartrate, and a butorphanol-perzinfotel combination on the minimum alveolar concentration of isoflurane in cats.
R. Zwijnenberg
,
Carlos L del Rio
,
R. Pollet
,
W. Muir
American Journal of Veterinary Research
2010
Corpus ID: 207384291
OBJECTIVE To determine the effects of perzinfotel, butorphanol, and their combination on the minimal alveolar concentration (MAC…
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2009
2009
Prodrugs of perzinfotel with improved oral bioavailability.
R. Baudy
,
J. Butera
,
+15 authors
W. Childers
Journal of Medicinal Chemistry
2009
Corpus ID: 37209444
Previous studies with perzinfotel (1), a potent, selective, competitive NMDA receptor antagonist, showed it to be efficacious in…
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2009
2009
Effects of intravenous administration of perzinfotel, fentanyl, and a combination of both drugs on the minimum alveolar concentration of isoflurane in dogs.
Y. Ueyama
,
P. Lerche
,
C. Mark Eppler
,
W. W. Muir
American Journal of Veterinary Research
2009
Corpus ID: 9860198
OBJECTIVE-To determine the effects of IV administration of perzinfotel and a perzinfotel-fentanyl combination on the minimum…
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2007
2007
Effects of perzinfotel on the minimum alveolar concentration of isoflurane in dogs.
Tokiko Kushiro
,
A. Wiese
,
M. Eppler
,
W. Muir
American Journal of Veterinary Research
2007
Corpus ID: 6717621
OBJECTIVE To determine the effect of IV administration of perzinfotel on the minimum alveolar concentration (MAC) of isoflurane…
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2005
2005
Pharmacological characterization of antiepileptic drugs and experimental analgesics on low magnesium-induced hyperexcitability in rat hippocampal slices
Robert L. Arias
,
M. Bowlby
Brain Research
2005
Corpus ID: 35000466
2005
2005
Effects of the N-Methyl-d-aspartate Receptor Antagonist Perzinfotel [EAA-090; [2-(8,9-Dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)-ethyl]phosphonic Acid] on Chemically Induced Thermal…
M. Brandt
,
T. Cummons
,
L. Potestio
,
S. Sukoff
,
S. Rosenzweig-Lipson
Journal of Pharmacology and Experimental…
2005
Corpus ID: 12989500
Perzinfotel [EAA-090; [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)-ethyl]phosphonic acid] is a selective, competitive N…
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2004
2004
Characterization of Two Novel N-Methyl-D-aspartate Antagonists: EAA-090 (2-[8,9-Dioxo-2,6-diazabicyclo [5.2.0]non-1(7)-en2-yl]ethylphosphonic Acid) and EAB-318 (R-α-Amino-5-chloro-1-(phosphonomethyl…
Lucy Sun
,
D. Chiu
,
+6 authors
S. Lin
Journal of Pharmacology and Experimental…
2004
Corpus ID: 25505657
Two novel N-methyl-d-aspartate (NMDA) antagonists with unique chemical structures, EAA-090 (2-[8,9-dioxo-2, 6-diazabicyclo[5.2.0…
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2002
2002
EAA-090. Neuroprotectant competitive NMDA antagonist
W. Childers
,
M. Abou-Gharbia
,
J. Moyer
,
M. Zaleska
2002
Corpus ID: 102482549
EAA-090 is a novel squaric acid amide derivative that has been identified as a potential treatment for the ischemic brain damage…
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Highly Cited
1998
Highly Cited
1998
Design and synthesis of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)-ethyl]phosphonic acid (EAA-090), a potent N-methyl-D-aspartate antagonist, via the use of 3-cyclobutene-1,2-dione as an…
W. Kinney
,
M. Abou-Gharbia
,
+7 authors
J. Moyer
Journal of Medicinal Chemistry
1998
Corpus ID: 23958918
The diazabicyclic amino acid phosphonate 15, [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)ethyl]phosphonic acid, was…
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