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E 5531

Known as: E-5531, E5531 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Lipid A
analogs & derivatives

Papers overview

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2017
2017
Innate immune-stimulatory activity of Porphyromonas gingivalis fimbriae is eliminated by phase separation using Triton X-114.
2007
2007
The cellular Toll-like receptor 4 antagonist E5531 can act as an agonist in horse whole blood.
Highly Cited
2001
Highly Cited
2001
A Novel Synthetic Acyclic Lipid A-like Agonist Activates Cells via the Lipopolysaccharide/Toll-like Receptor 4 Signaling Pathway*
ER-112022 is a novel acyclic synthetic lipid A analog that contains six symmetrically organized fatty acids on a noncarbohydrate… 
2000
2000
The Effect of Divalent Cations on the Membrane Properties and Pharmacokinetics in Rat of the Lipid A Analogue E5531
To obtain information on the effects of Ca2+ on the membrane properties of the lipid A analogue E5531, we have determined the… 
1999
1999
The effect of the lipid A analog, E5531 on fever induced by endotoxin from Escherichia coli.
E5531 is a specific lipid A antagonist and is expected to be a drug for the treatment of septic shock. The LAL (limulus amebocyte… 
1999
1999
Control of the Dispersing Process and Pharmacokinetics in Rats for Lipid A Analogue, E5531
E5531 is a synthetic disaccharide analogue of lipid A which has a low toxicity but retains the ability to reduce production of… 
1998
1998
The effect of the lipid A analog E5531 on phospholipid membrane properties
Review
1998
Review
1998
[Sepsis and organ failure--its pathogenesis and treatment].
Sepsis, septic shock, and multiple organ dysfunction are heterogeneous and sophisticated clinical syndromes which result from the… 
1995
1995
E5531, AN ENDOTOXIN ANTAGONIST, BLOCKS THE HYPERDYNAMIC AND DEPRESSANT CARDIOVASCULAR EFFECTS OF ENDOTOXIN IN HEALTHY SUBJECTS
1995
1995
EFFECT OF E5531 ON SYSTEMIC RESPONSES TO ENDOTOXIN IN HEALTHY VOLUNTEERS
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