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Duxon

Known as: PHPMA polymer, poly(N-(2-hydroxypropyl)methacrylamide), polyHPMA 
National Institutes of Health

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Broader (1)

Polymethacrylic Acids

Papers overview

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2018
2018
Enzyme/pH-sensitive polyHPMA-DOX conjugate as a biocompatible and efficient anticancer agent.
In this study, to enhance the therapeutic function and reduce the side-effects of doxorubicin (DOX), a biodegradable N-(2… 
2014
2014
Abstract 4485: Synthesis of targeted docetaxel-polymer conjugate and its anti-tumor efficacy
Over the last decade, it has been shown that nanopolymer therapeutics can be engineered to target cancer cells specifically and… 
2014
2014
FRET Imaging Trackable Long-Circulating Biodegradable Nanomedicines for Ovarian Carcinoma Therapy
for the 3 Symposium on Innovative Polymers for Controlled Delivery Design and Synthesis of FRET-Trackable HPMA-Based… 
2013
2013
Double selective antitumor action of pirarubicin-conjugated N-( 2-hydroxypropyl ) methacrylamide copolymer
SUMMARY In this study, we synthesized pirarubicin (THP)conjugated poly-N-(2-hydroxypropyl) methacrylamide (PHPMA) containing acid… 
2001
2001
N-(2-hydroxypropyl)methacrylamide copolymer-6-(3-aminopropyl)-ellipticine conjugates. Synthesis, in vitro, and preliminary in vivo evaluation.
Ellipticine derivatives have potential as anticancer drugs. Their clinical use has been limited, however, by poor solubility and… 
2000
2000
Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic-hydrophilic copolymers.
1988
1988
Pharmacological evaluation of the toxicity after repeated administration of synthetic colloid solution of Duxon
1986
1986
Effect of a synthetic poly N-(2-hydroxypropyl)methacrylamide (Duxon) on haemopoiesis and graft-versus-host reaction.
A synthetic polymer, Duxon, was developed and tested as a substitute of blood plasma for transfusion purposes. Tests of this… 
1980
1980
Immunosuppressive effects of a synthetic polymer poly N-(2-hydroxypropyl)methacrylamide (Duxon).
Poly N-(2-hydroxypropyl)methacrylamide (Duxon) was studied as a substitute of blood plasma and was found to prolong significantly… 
1980
1980
[Duxon--a new Czechoslovak--made infusion solution--an experimental contribution to biological evaluation].
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