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Dutasteride

Known as: (5alpha,17beta)-N-(2,5-Bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide, 17beta-N-(2,5-bis(trifluoromethyl))phenyl-carbamoyl-4-aza-5alpha-androst-1-en-3-one, Dutasteride [Chemical/Ingredient] 
A synthetic 4-azasteroid compound. Dutasteride competitively and specifically binds to isoenzymes 1 and 2 of 5 alpha-reductase, forming stable enzyme… 
National Institutes of Health

Related topics

Related topics

19 relations

Broader (1)

5-alpha Reductase Inhibitors

Narrower (4)

AvodartGG 745GI198745Jalyn
ChildDrug AllergyDutasteride / tamsulosinDutasteride 0.5 MG

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The effect of dutasteride on MRI-defined prostate cancer lesions: MAPPED (Magnetic resonance imaging in Primary Prostate Cancer after Exposure to Dutasteride) - a randomized placebo-controlled…
PURPOSE: Dutasteride is licensed for symptomatic benign prostatic hyperplasia, and has been associated with a lower progression… 
2016
2016
Toxicología aguda en conejos del D-005, extracto lipídico del fruto de Acrocomia Crispa (palma corojo)
D-005, is a lipid extract from the fruits of Acrocomia crispa (corojo palm tree) (Arecaceae), palm specie endemic from Cuba that… 
2015
2015
DEVELOPMENT AND VALIDATION OF STABILITY INDICATING METHOD FOR THE SIMULTANEOUS DETERMINATION OF TAMSULOSIN AND DUTASTERIDE IN BULK DRUGS AND PHARMACEUTICAL DOSAGE FORMS USING UV SPECTROPHOTOMETRIC…
A new simple, precise method for simultaneous estimation of Tamsulosin and Dutasteride using UV spectroscopy has been developed… 
Review
2014
Review
2014
Novel RP-HPLC Method for Simultaneous Estimation of Silodosin and Dutasteride in Multiunit Solid Dosage Form.
Silodosin and Dutasteride both are approved drugs by USFDA (Food & Drug Administration). On literature survey, it was found that… 
2014
2014
The Effect of 5 a-reductase Inhibition with Finasteride and Dutasteride on Bone Mineral Density in Older Men with Benign Prostatic Hyperplasia
Testosterone is converted to dihyrotestosterone by two isoenzymes of 5a-reductase. Finasteride and dutasteride are 5a-reductase… 
2014
2014
Simultaneous estimation of alfuzosin hydrochloride and dutasteride by validated RP -HPLC method
This research paper describes validated reverse phase liquid chromatographic method for the simultaneous estimation of alfuzosin… 
2012
2012
MORPHOLOGICAL ALTERATIONS OF PROSTATE TISSUE, UPON DUTASTERIDE THERAPY INFLUENCE
In this study authors carried out the comparative analysis of prostatic tissue morphology in patients with BPH on prior medical… 
2010
2010
Development and validation of RP-HPLC method for simultaneous estimationof Alfuzosin Hydrochloride and Dutasteride in pharmaceutical dosage form
A simple, rapid, specific and sensitive Reverse Phase-HPLC method has been developed and validated for the simultaneous… 
Review
2010
Review
2010
The Mechanism of Androgen Deprivation and the Androgen Receptor
Prostate cancer is a major cause of cancer-related deaths in American men. The development and growth of prostate cancer depends… 
2006
2006
Chemopreventive trials in urologic cancer.
Cancer prevention uses natural, synthetic, or biological chemical agents to reverse, suppress, or prevent carcinogenic…