Skip to search formSkip to main contentSkip to account menu

Dutasteride

Known as: (5alpha,17beta)-N-(2,5-Bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide, 17beta-N-(2,5-bis(trifluoromethyl))phenyl-carbamoyl-4-aza-5alpha-androst-1-en-3-one, Dutasteride [Chemical/Ingredient] 
A synthetic 4-azasteroid compound. Dutasteride competitively and specifically binds to isoenzymes 1 and 2 of 5 alpha-reductase, forming stable enzyme… 
National Institutes of Health

Related topics

Related topics

19 relations

Broader (1)

5-alpha Reductase Inhibitors

Narrower (4)

AvodartGG 745GI198745Jalyn
ChildDrug AllergyDutasteride / tamsulosinDutasteride 0.5 MG

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Clinical judgment versus biomarker prostate cancer gene 3: which is best when determining the need for repeat prostate biopsy?
2013
2013
Formulation and in vivo Evaluation of a Self-Microemulsifying Drug Delivery System of Dutasteride
Abstract This study aimed to develop an effective formulation to improve the solubility and oral absorption of dutasteride by… 
2012
2012
Prostate biopsy in response to a change in nadir prostate specific antigen of 0.4 ng/ml after treatment with 5α-reductase inhibitors markedly enhances the detection rate of prostate cancer.
2009
2009
Adalimumab treats psoriasis in patients previously treated with etanercept: a case series.
2007
2007
Quantifying the impact of prostate volumes, number of biopsy cores and 5alpha-reductase inhibitor therapy on the probability of prostate cancer detection using mathematical modeling.
2007
2007
Finasteride to Evaluate the Efficacy of Dutasteride in the Management of Patients with Lower Urinary Tract Symptoms and Enlarged Prostate
Patients with lower urinary tract symptoms and enlarged prostate were randomized to receive, in a double blind fashion, either… 
Review
2006
Review
2006
Update on Prostate Cancer Chemoprevention
Background. Prostate cancer is the most common type of cancer and the second leading cause of cancer‐related deaths in American… 
2006
2006
Oral testosterone in oil: pharmacokinetic effects of 5alpha reduction by finasteride or dutasteride and food intake in men.
Oral administration of 400 mg of testosterone (T) in oil, when combined with the 5alpha reductase inhibitor dutasteride (D… 
2004
2004
Dutasteride, the dual 5alpha-reductase inhibitor, inhibits androgen action and promotes cell death in the LNCaP prostate cancer cell line.
BACKGROUND Reduction of T to DHT by 5alphaR in the prostate enhances androgenic activity for most targets. Inhibition of 5alphaR… 
2003
2003
The Finnish version of The National Institutes Of Health Chronic Prostatitis Symptom Index correlates well with the visual pain scale: translation and results of a modified linguistic validation…
Authors from Finland have assessed a version in their language of the National Institutes of Health‐Chronic Prostatitis Symptom… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)