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Dutasteride

Known as: (5alpha,17beta)-N-(2,5-Bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide, 17beta-N-(2,5-bis(trifluoromethyl))phenyl-carbamoyl-4-aza-5alpha-androst-1-en-3-one, Dutasteride [Chemical/Ingredient] 
A synthetic 4-azasteroid compound. Dutasteride competitively and specifically binds to isoenzymes 1 and 2 of 5 alpha-reductase, forming stable enzyme… 
National Institutes of Health

Related topics

Related topics

19 relations

Broader (1)

5-alpha Reductase Inhibitors

Narrower (4)

AvodartGG 745GI198745Jalyn
ChildDrug AllergyDutasteride / tamsulosinDutasteride 0.5 MG

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The Role of Dutasteride in Acute Prostatic Haematuria
Background: Dutasteride has been found to reduce chronic prostatic bleeding and when taken 2 - 6 weeks preoperatively reduces… 
2012
2012
Role of dutasteride in pre‐clinical ETS fusion‐positive prostate cancer models
Androgens play a crucial role in prostate cancer, hence the androgenic pathway has become an important target of therapeutic… 
2010
2010
Development and validation of RP-HPLC method for simultaneous estimationof Alfuzosin Hydrochloride and Dutasteride in pharmaceutical dosage form
A simple, rapid, specific and sensitive Reverse Phase-HPLC method has been developed and validated for the simultaneous… 
2010
2010
Dutasteride prevents the growth response to testosterone in benign and androgen-sensitive malignant prostate cells.
We show that the dual 5-α reductase enzyme inhibitor dutasteride prevents enhanced growth of both benign and malignant prostate… 
Review
2010
Review
2010
Evidence-based medicine: time for transition and translation (to practice)
It is a time of change for evidence-based medicine (EBM, the field) and for EBM (the journal). With this issue of EBM I become… 
Review
2010
Review
2010
The Mechanism of Androgen Deprivation and the Androgen Receptor
Prostate cancer is a major cause of cancer-related deaths in American men. The development and growth of prostate cancer depends… 
2008
2008
Determination of Dutasteride from its Bulk Drug and Pharmaceutical Preparations by High Performance Thin Layer Chromatography
A rapid, simple and sensitive high-performance thin layer chromatographic method (HPTLC) has been developed to assay dutasteride… 
2006
2006
Chemopreventive trials in urologic cancer.
Cancer prevention uses natural, synthetic, or biological chemical agents to reverse, suppress, or prevent carcinogenic… 
2004
2004
The Use of Nomograms for Selecting BPH Candidates for Dutasteride Therapy.
Recent studies have discussed the benefits of medical therapy for benign prostatic hyperplasia (BPH), but have not provided… 
2003
2003
A VALIDATED SPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF DUTASTERIDE IN BULK DRUG AND PHARMACEUTICAL FORMULATIONS
  • Kamila
  • 2003
  • Corpus ID: 212574559
A simple, sensitive and accurate UV spectrophotometric method has been developed for the determination of dutasteride in raw… 
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