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Dutasteride
Known as:
(5alpha,17beta)-N-(2,5-Bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
, 17beta-N-(2,5-bis(trifluoromethyl))phenyl-carbamoyl-4-aza-5alpha-androst-1-en-3-one
, Dutasteride [Chemical/Ingredient]
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A synthetic 4-azasteroid compound. Dutasteride competitively and specifically binds to isoenzymes 1 and 2 of 5 alpha-reductase, forming stable enzyme…
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National Institutes of Health
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Related topics
Related topics
19 relations
Broader (1)
5-alpha Reductase Inhibitors
Narrower (4)
Avodart
GG 745
GI198745
Jalyn
Child
Drug Allergy
Dutasteride / tamsulosin
Dutasteride 0.5 MG
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The Role of Dutasteride in Acute Prostatic Haematuria
V. Ofuru
,
C. Obiorah
2017
Corpus ID: 53056210
Background: Dutasteride has been found to reduce chronic prostatic bleeding and when taken 2 - 6 weeks preoperatively reduces…
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2016
2016
Is Transurethral Resection of Prostate Made Safer by Preoperative Dutasteride Therapy? A Randomized Controlled Trial
A. Jamal
,
P. Srinivasarao
,
L. Dorairajan
,
Santosh Kumar
2016
Corpus ID: 78054081
Introduction: Bleeding and hyponatremia are important complications of transurethral resection of the prostate (TURP). 5-alpha…
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Review
2014
Review
2014
Novel RP-HPLC Method for Simultaneous Estimation of Silodosin and Dutasteride in Multiunit Solid Dosage Form.
Hardik Shah
,
A. Khandar
,
Shirish Deshpande
,
S. Bagade
2014
Corpus ID: 97915598
Silodosin and Dutasteride both are approved drugs by USFDA (Food & Drug Administration). On literature survey, it was found that…
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2012
2012
Role of dutasteride in pre‐clinical ETS fusion‐positive prostate cancer models
Bushra Ateeq
,
A. Vellaichamy
,
+5 authors
S. Varambally
The Prostate
2012
Corpus ID: 43832815
Androgens play a crucial role in prostate cancer, hence the androgenic pathway has become an important target of therapeutic…
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2010
2010
Development and validation of RP-HPLC method for simultaneous estimationof Alfuzosin Hydrochloride and Dutasteride in pharmaceutical dosage form
Shivprasad S. Deshmukh
,
S. Havele
,
Vaishali V. Musale
,
S. Dhaneshwar
2010
Corpus ID: 99208942
A simple, rapid, specific and sensitive Reverse Phase-HPLC method has been developed and validated for the simultaneous…
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Review
2010
Review
2010
Evidence-based medicine: time for transition and translation (to practice)
R. Saitz
Evidence-Based Medicine
2010
Corpus ID: 21219621
It is a time of change for evidence-based medicine (EBM, the field) and for EBM (the journal). With this issue of EBM I become…
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Review
2010
Review
2010
The Mechanism of Androgen Deprivation and the Androgen Receptor
S. Bayraktar
2010
Corpus ID: 168883
Prostate cancer is a major cause of cancer-related deaths in American men. The development and growth of prostate cancer depends…
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2008
2008
Determination of Dutasteride from its Bulk Drug and Pharmaceutical Preparations by High Performance Thin Layer Chromatography
Vinayak T. Vele
,
Vishal Choudhari
,
S. S. Prabhune
2008
Corpus ID: 99094400
A rapid, simple and sensitive high-performance thin layer chromatographic method (HPTLC) has been developed to assay dutasteride…
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2006
2006
Chemopreventive trials in urologic cancer.
Vahagn R Ashughyan
,
S. Marihart
,
B. Djavan
Reviews in urology
2006
Corpus ID: 22066797
Cancer prevention uses natural, synthetic, or biological chemical agents to reverse, suppress, or prevent carcinogenic…
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2003
2003
A VALIDATED SPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF DUTASTERIDE IN BULK DRUG AND PHARMACEUTICAL FORMULATIONS
Kamila
2003
Corpus ID: 212574559
A simple, sensitive and accurate UV spectrophotometric method has been developed for the determination of dutasteride in raw…
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