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Dutasteride

Known as: (5alpha,17beta)-N-(2,5-Bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide, 17beta-N-(2,5-bis(trifluoromethyl))phenyl-carbamoyl-4-aza-5alpha-androst-1-en-3-one, Dutasteride [Chemical/Ingredient] 
A synthetic 4-azasteroid compound. Dutasteride competitively and specifically binds to isoenzymes 1 and 2 of 5 alpha-reductase, forming stable enzyme… 
National Institutes of Health

Related topics

Related topics

19 relations

Broader (1)

5-alpha Reductase Inhibitors

Narrower (4)

AvodartGG 745GI198745Jalyn
ChildDrug AllergyDutasteride / tamsulosinDutasteride 0.5 MG

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Is Transurethral Resection of Prostate Made Safer by Preoperative Dutasteride Therapy? A Randomized Controlled Trial
Introduction: Bleeding and hyponatremia are important complications of transurethral resection of the prostate (TURP). 5-alpha… 
2016
2016
Toxicología aguda en conejos del D-005, extracto lipídico del fruto de Acrocomia Crispa (palma corojo)
D-005, is a lipid extract from the fruits of Acrocomia crispa (corojo palm tree) (Arecaceae), palm specie endemic from Cuba that… 
Review
2014
Review
2014
Novel RP-HPLC Method for Simultaneous Estimation of Silodosin and Dutasteride in Multiunit Solid Dosage Form.
Silodosin and Dutasteride both are approved drugs by USFDA (Food & Drug Administration). On literature survey, it was found that… 
2014
2014
The Effect of 5 a-reductase Inhibition with Finasteride and Dutasteride on Bone Mineral Density in Older Men with Benign Prostatic Hyperplasia
Testosterone is converted to dihyrotestosterone by two isoenzymes of 5a-reductase. Finasteride and dutasteride are 5a-reductase… 
2010
2010
Development and validation of RP-HPLC method for simultaneous estimationof Alfuzosin Hydrochloride and Dutasteride in pharmaceutical dosage form
A simple, rapid, specific and sensitive Reverse Phase-HPLC method has been developed and validated for the simultaneous… 
Review
2010
Review
2010
The Mechanism of Androgen Deprivation and the Androgen Receptor
Prostate cancer is a major cause of cancer-related deaths in American men. The development and growth of prostate cancer depends… 
2008
2008
Determination of Dutasteride from its Bulk Drug and Pharmaceutical Preparations by High Performance Thin Layer Chromatography
A rapid, simple and sensitive high-performance thin layer chromatographic method (HPTLC) has been developed to assay dutasteride… 
2006
2006
Chemopreventive trials in urologic cancer.
Cancer prevention uses natural, synthetic, or biological chemical agents to reverse, suppress, or prevent carcinogenic… 
2003
2003
A VALIDATED SPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF DUTASTERIDE IN BULK DRUG AND PHARMACEUTICAL FORMULATIONS
  • Kamila
  • 2003
  • Corpus ID: 212574559
A simple, sensitive and accurate UV spectrophotometric method has been developed for the determination of dutasteride in raw… 
1992
1992
Medicament for prevention of prostatic carcinoma by 17beta-acyl-4-aza-5alpha-androst-1-en-3-one
  • G. GormleyE. Stonerエリザベス・ストナーグレン・ジエイ・ゴームリー
  • 1992
  • Corpus ID: 103710302
PURPOSE: To prepare a medicament contg. a new testosterone 5α-reductase inhibiting agent and useful for the prevention of human…