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Drug Evaluation, Preclinical

Known as: Preclinical Drug Evaluations, Evaluation Studies, Drug, Pre-Clinical, Screening, Drug 
Preclinical testing of drugs in experimental animals or in vitro for their biological and toxic effects and potential clinical applications.
National Institutes of Health

Papers overview

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Review
2006
Review
2006
Designing and developing truly tumor-specific prodrugs remains a challenge in the field of cancer chemotherapy. Active targeting… 
Review
2005
Review
2005
DIMSCAN is a semiautomatic fluorescence-based digital image microscopy system that quantifies relative total (using a DNA stain… 
Review
2002
Review
2002
The lysosomal storage disorders (LSD) are monogenic inborn errors of metabolism with heterogeneous pathophysiology and clinical… 
1998
1998
Antibody-directed, superantigen-induced cytotoxicity has been shown to have potent in vitro and in vivo antitumor effects in… 
1998
1998
PURPOSE A phase I, multicenter trial of the thymidylate synthase (TS) inhibitor THYMITAQ (nolatrexed dihydrochloride; Agouron… 
Highly Cited
1994
Highly Cited
1994
Clinical trials combining paclitaxel with other active chemotherapy agents are currently underway. In vitro preclinical studies…