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Drug Design

Known as: design drug, Design, Drug, Designs, Drug 
The molecular designing of drugs for specific purposes (such as DNA-binding, enzyme inhibition, anti-cancer efficacy, etc.) based on knowledge of… 
National Institutes of Health

Related topics

Related topics

4 relations
Designer Drugsanalog drug

Narrower (1)

Drug Modeling

Broader (1)

Substance of abuse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Update 1 of: Recent progress in development of dopamine receptor subtype-selective agents: potential therapeutics for neurological and psychiatric disorders.
Subtype-Selective Agents: Potential Therapeutics for Neurological and Psychiatric Disorders Na Ye,† John L. Neumeyer,‡ Ross J… 
Review
2010
Review
2010
The role of water molecules in computational drug design.
Although water molecules are small and only consist of two different atom types, they play various roles in cellular systems… 
Review
2010
Review
2010
De novo drug design.
Computer-assisted molecular design supports drug discovery by suggesting novel chemotypes and compound modifications for lead… 
Highly Cited
2009
Highly Cited
2009
Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90.
Although therapeutically targeting a single signaling pathway that drives tumor development and/or progression has been effective… 
Review
2008
Review
2008
Molecule-pharmacophore superpositioning and pattern matching in computational drug design.
Highly Cited
2007
Highly Cited
2007
Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity.
Using d-xylose as an appropriate chiral precursor, we have synthesized active neuraminidase inhibitor oseltamivir, antiflu drug… 
Review
2005
Review
2005
Nanostructure-mediated drug delivery.
  • G. Hughes
  • Disease-a-month : DM
  • 2005
  • Corpus ID: 858282
Review
2003
Review
2003
Ace revisited: A new target for structure-based drug design
Current-generation angiotensin-converting enzyme (ACE) inhibitors are widely used for cardiovascular diseases, including high… 
Review
2003
Review
2003
Differential effects of cell cycle regulatory protein p21(WAF1/Cip1) on apoptosis and sensitivity to cancer chemotherapy.
Review
1998
Review
1998
CNS Drug Design Based on Principles of Blood‐Brain Barrier Transport
Abstract: Lipid‐soluble small molecules with a molecular mass under a 400–600‐Da threshold are transported readily through the… 
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