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Designer Drugs

Known as: Drugs, Designer, Customized Drugs, Drugs, Customized 
Drugs designed and synthesized, often for illegal street use, by modification of existing drug structures (e.g., amphetamines). Of special interest… 
National Institutes of Health

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2,5-Dimethoxy-4-methylamphetamineEcstasy - drug
Drug DependenceDrug DesignDrug abuserDrug usage

Papers overview

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2015
2015
Mapping the precision of genome editing
Genome-wide, unbiased methods provide a comprehensive picture of off-target cleavage by engineered nucleases. 
2015
2015
Analysis of new designer drugs in post-mortem blood using high-resolution mass spectrometry.
An analytical method was developed and validated for the purpose of detecting and quantifying 37 new designer drugs including… 
2015
2015
Discriminative-stimulus effects of second generation synthetic cathinones in methamphetamine-trained rats.
Highly Cited
2013
Highly Cited
2013
Characteristics of the designer drug and synthetic cannabinoid receptor agonist AM-2201 regarding its chemistry and metabolism.
Aminoalkylindoles, a subclass of synthetic cannabinoid receptor agonists, show an extensive and complex metabolism in vivo, and… 
Review
2010
Review
2010
Metabolism of designer drugs of abuse: an updated review.
This paper reviews the metabolism of new designer drugs of abuse that have emerged on the black market during the last years and… 
Highly Cited
2010
Highly Cited
2010
Identification and quantitation of two cannabimimetic phenylacetylindoles JWH-251 and JWH-250, and four cannabimimetic naphthoylindoles JWH-081, JWH-015, JWH-200, and JWH-073 as designer drugs in…
Six cannabimimetic indoles have been identified as adulterants in herbal or chemical products being sold illegally in Japan, with… 
2008
2008
Metabolism and toxicological detection of the designer drug 4-chloro-2,5-dimethoxyamphetamine in rat urine using gas chromatography-mass spectrometry
Studies are described on the metabolism and the toxicological analysis of the amphetamine-derived designer drug 4-chloro-2,5… 
Highly Cited
2003
Highly Cited
2003
New designer drug 1-(3-trifluoromethylphenyl) piperazine (TFMPP): gas chromatography/mass spectrometry and liquid chromatography/mass spectrometry studies on its phase I and II metabolism and on its…
Studies are described on the phase I and II metabolism and the toxicological analysis of the piperazine-derived designer drug 1… 
Review
2000
Review
2000
Amphetamine designer drugs - an overview and epidemiology.
1999
1999
Active transport by customized β–barrels
  • K. Postle
  • Nature Structural Biology
  • 1999
  • Corpus ID: 94262237
The crystal structures of two bacterial outer membrane transport proteins — FepA and FhuA — put the field on a solid molecular… 
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