Doxycycline

Known as: 6-alpha-deoxy-5-oxytetracycline, 6alpha-deoxy-5-oxytetracycline, 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,12aalpha))- 
A synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity. Doxycycline binds to the 30S ribosomal subunit, possibly to… (More)

Topic mentions per year

Topic mentions per year

1943-2018
020040060019432017

Papers overview

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Highly Cited
2009
Highly Cited
2009
Transgenic expression of just four defined transcription factors (c-Myc, Klf4, Oct4 and Sox2) is sufficient to reprogram somatic… (More)
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Highly Cited
2008
Highly Cited
2008
Ectopic expression of the transcription factors Oct4, Sox2, c-Myc, and Klf4 in fibroblasts generates induced pluripotent stem… (More)
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Highly Cited
2006
Highly Cited
2006
We investigated the effects of corticosteroid and doxycycline on expression of matrix metalloproteinase (MMP)-9 and inflammatory… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE Angiotensin II (AngII) infusion into hyperlipidemic mice leads to the rapid formation of atherosclerotic lesions and… (More)
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Highly Cited
2002
Highly Cited
2002
Normal developmental events such as puberty, pregnancy, and parity influence the susceptibility of the mammary gland to… (More)
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Highly Cited
2000
Highly Cited
2000
Regulatory elements that control tetracycline resistance in Escherichia coli were previously converted into highly specific… (More)
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Highly Cited
1998
Highly Cited
1998
Ischemic stroke is the most common life-threatening neurological disease and has limited therapeutic options. One component of… (More)
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Highly Cited
1997
Highly Cited
1997
Neutrophil collagenase (matrix metalloproteinase-8 or MMP-8) is regarded as being synthesized exclusively by polymorphonuclear… (More)
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Highly Cited
1996
Highly Cited
1996
The tet regulatory system in which doxycycline (dox) acts as an inducer of specifically engineered RNA polymerase II promoters… (More)
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Highly Cited
1995
Highly Cited
1995
A transcriptional transactivator was developed that fuses the VP16 activation domain with a mutant Tet repressor from Escherichia… (More)
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