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Dorzolamide hydrochloride

The hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of… 
National Institutes of Health

Related topics

Related topics

6 relations
Drug AllergyGlaucoma, Open-AngleKidney Failuredorzolamide 20 MG/ML / Timolol 5 MG/ML Ophthalmic Solution

Narrower (1)

Trusopt

Broader (1)

dorzolamide

Papers overview

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2003
2003
Voltammetric and HPLC determination of dorzolamide hydrochloride in eye drops.
The behaviour of dorzolamide hydrochloride (DOR) was investigated at a glassy carbon electrode in different buffer systems using… 
2003
2003
Unoprostone as adjunctive therapy to timolol: a double masked randomised study versus brimonidine and dorzolamide
Aims: To compare the safety and efficacy of unoprostone, brimonidine, and dorzolamide as adjunctive therapy to timolol in… 
1999
1999
A randomized study of dorzolamide in the prevention of elevated intraocular pressure after anterior segment laser surgery. Dorzolamide Laser Study Group.
PURPOSE To evaluate the efficacy of 2% dorzolamide hydrochloride opthalmic solution in preventing spikes in intraocular pressure… 
Highly Cited
1998
Highly Cited
1998
Effect of dorzolamide on corneal endothelial function in normal human eyes.
PURPOSE To assess the effects of dorzolamide hydrochloride, a topical carbonic anhydrase inhibitor, on corneal endothelial… 
1998
1998
The effect of dorzolamide on aqueous humor dynamics in normal human subjects during sleep.
Highly Cited
1997
Highly Cited
1997
Comparison of dorzolamide and timolol as suppressors of aqueous humor flow in humans.
OBJECTIVES To measure the effectiveness of topical 2% dorzolamide hydrochloride (Trusopt, Merck & Co Inc, Whitehouse Station, NJ… 
1997
1997
Topical 2.0% dorzolamide vs oral acetazolamide for prevention of intraocular pressure rise after neodymium:YAG laser posterior capsulotomy.
OBJECTIVE To compare the efficacy and safety of topical 2.0% dorzolamide hydrochloride with oral acetazolamide in preventing… 
Review
1997
Review
1997
Economic evaluation of dorzolamide vs. pilocarpine for primary open-angle glaucoma.
This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a… 
Review
1997
Review
1997
Preclinical Ocular Irritation Findings with Dorzolamide Hydrochloride
AbstractThe results of 11 ocular irritation studies in rabbits, dogs, and monkeys treated with 2,3, or 4% dorzolamide… 
Highly Cited
1996
Highly Cited
1996
Continuous intraocular pressure measurement by telemetry in alpha-chymotrypsin-induced glaucoma model in the rabbit: effects of timolol, dorzolamide, and epinephrine.
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