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Dorzolamide hydrochloride

The hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Background: Several in situ gel-forming systems have been developed to prolong the precorneal residence time of a drug and to… Expand
Highly Cited
2009
Highly Cited
2009
Dilutable nanoemulsions are potent drug delivery vehicles for ophthalmic use due to their numerous advantages as sustained effect… Expand
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE To compare the dorzolamide-timolol fixed combination twice daily to its components, timolol maleate and dorzolamide… Expand
Highly Cited
1997
Highly Cited
1997
Purpose: To compare the effectiveness of topical dorzolamide hydrochloride (Trusopt, Merck and Co., Inc., West Point, PA), a… Expand
Highly Cited
1997
Highly Cited
1997
OBJECTIVE To determine the relationship between central corneal thickness (CCT) and applanation intraocular pressure (IOP) in… Expand
Review
1996
Review
1996
  • M. F. Sugrue
  • Journal of ocular pharmacology and therapeutics…
  • 1996
  • Corpus ID: 19818177
Dorzolamide hydrochloride (S,S-5,6-dihydro-4H-4-ethylamino-6-methylthieno [2,3-b]thiopyran-2-sulfonamide-7,7-dioxide HCl; MK-507… Expand
Highly Cited
1996
Highly Cited
1996
The aim of this study was to set-up and validate the use of a radio-telemetry system in order to record IOP in chronic ocular… Expand
Highly Cited
1996
Highly Cited
1996
PURPOSE To investigate the efficacy and dose-response relationship of three concentrations (0.2%, 0.7%, and 2.0%) of dorzolamide… Expand
Highly Cited
1995
Highly Cited
1995
OBJECTIVE To investigate the safety profile and efficacy of 2.0% dorzolamide hydrochloride, when administered three times daily… Expand
Highly Cited
1993
Highly Cited
1993
OBJECTIVE To investigate the activity and local and systemic safety of the topical carbonic anhydrase inhibitor, dorzolamide… Expand