Dopal

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1960-2018
024619602018

Papers overview

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2016
2016
Parkinson's disease has long been known to involve the loss of dopaminergic neurons in the substantia nigra and the coincidental… (More)
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2015
2015
Oxidative deamination of dopamine produces the highly toxic aldehyde 3,4-dihydroxyphenylacetaldehyde (DOPAL), enhanced production… (More)
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2014
2014
Parkinson disease (PD) features profound striatal dopamine depletion and Lewy bodies containing abundant precipitated alpha… (More)
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2013
2013
Intra-neuronal metabolism of dopamine (DA) begins with production of 3,4-dihydroxyphenylacetaldehyde (DOPAL),which is toxic… (More)
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2010
2010
BACKGROUND The etiology of Parkinson disease (PD) has yet to be fully elucidated. We examined the consequences of injections of 3… (More)
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2003
2003
In Parkinson's disease (PD), there is a highly selective loss of dopamine (DA) neurons in the substantia nigra (SN) greater than… (More)
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2001
2001
Parkinson's disease (PD) is a major cause of age-related morbidity and mortality, present in nearly 1% of individuals at ages 70… (More)
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2001
2001
3,4-Dihydroxyphenylacetaldehyde (DOPAL) and 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL), the monoamine oxidase (MAO) metabolites… (More)
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1987
1987
Aldehyde dehydrogenase (ALDH, EC 1.2.1.3), has been shown to be the most important enzyme for DOPAL metabolism in human brain… (More)
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1987
1987
The metabolism of biogenic aldehydes was measured in different human blood fractions. Isolated erythrocytes, leukocytes… (More)
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