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Diversity Library

Collections of different molecules, often produced through combinatorial synthetic methods, used as a starting pool to screen against a desired… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
High-Throughput Screening Assays for Cancer Immunotherapy Targets: Ectonucleotidases CD39 and CD73
Production of adenosine in the extracellular tumor microenvironment elicits strong immunosuppression and is associated with tumor… 
2009
2009
Computer Aided Identification of Small Molecules Disrupting uPAR/α5β1- Integrin Interaction: A New Paradigm for Metastasis Prevention
Background Disseminated dormant cancer cells can resume growth and eventually form overt metastases, but the underlying molecular… 
2008
2008
Use of peptide analogue diversity library beads for increased depth of proteomic analysis: application to cerebrospinal fluid.
Biological samples can contain proteins with concentrations that span more than 10 orders of magnitude. Given the limited dynamic… 
2003
2003
Enrichment of a single clone from a high diversity library of phage-displayed antibodies by panning with Anopheles gambiae (Diptera: Culicidae) midgut homogenate
Abstract A high diversity library of recombinant human antibodies was selected on complex antigen mixtures from midguts of female… 
2002
2002
Structure-based screening as applied to human FABP4: a highly efficient alternative to HTS for hit generation.
The time-limiting step in HTS often is the development of an appropriate assay. In addition, hits from HTS fairly often turn out… 
2001
2001
Identification of Oligomerizing Peptides*
The AraC DNA binding domain is inactive in a monomeric form but can activate transcription from the arabinose operon promoters… 
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