Discontinuation (procedure)

Known as: discontinuation, discontinuations 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2018
010020019782018

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND The BRAF inhibitors vemurafenib and dabrafenib have shown efficacy as monotherapies in patients with previously… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Dabrafenib is an inhibitor of BRAF kinase that is selective for mutant BRAF. We aimed to assess its safety and… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Peginterferon-ribavirin therapy is the current standard of care for chronic infection with hepatitis C virus (HCV… (More)
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Highly Cited
2011
Highly Cited
2011
Sclerostin, an osteocyte-secreted protein, negatively regulates osteoblasts and inhibits bone formation. In this first-in-human… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Nilotinib has been shown to be a more potent inhibitor of BCR-ABL than imatinib. We evaluated the efficacy and safety… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Several studies have shown the efficacy, tolerability, and ease of administration of pemetrexed-an antifolate… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Tumor necrosis factor (TNF) is an important proinflammatory cytokine that mediates inflammatory synovitis and articular… (More)
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Highly Cited
2003
Highly Cited
2003
Treatments for invasive fungal infections remain unsatisfactory. We evaluated the efficacy, tolerability, and safety of… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND ACE inhibitors attenuate the detrimental effects of angiotensin II, and improve survival and reduce morbidity in… (More)
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Highly Cited
1999
Highly Cited
1999
CONTEXT Leflunomide is a reversible inhibitor of de novo pyrimidine synthesis shown to be effective in a phase 2 trial in 402… (More)
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