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Direct Sequencing

A technique used to identify the sequence of individual nucleobases in a single strand of DNA fragment template, which can be a plasmid insert… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The ability to efficiently and accurately determine genotypes is a keystone technology in modern genetics, crucial to studies… Expand
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Highly Cited
2008
Highly Cited
2008
The positioning of nucleosomes with respect to DNA plays an important role in regulating transcription. However, nucleosome… Expand
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Highly Cited
2008
Highly Cited
2008
Although whole-genome association studies using tagSNPs are a powerful approach for detecting common variants, they are… Expand
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Highly Cited
2006
Highly Cited
2006
The anti-epidermal growth factor receptor (anti-EGFR) cetuximab has been proven to be efficient in metastatic colorectal cancer… Expand
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Highly Cited
1996
Highly Cited
1996
We have examined the prothrombin gene as a candidate gene for venous thrombosis in selected patients with a documented familial… Expand
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Highly Cited
1995
Highly Cited
1995
Vol. 61, no. 3, p. 1104, column 2, 5 lines from the bottom: "each of the primers at a concentration of 1 mM" should read "each of… Expand
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Highly Cited
1994
Highly Cited
1994
Structural alterations of the apolipoprotein E (apo E) are known to influence the lipid metabolism. The three most common… Expand
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Highly Cited
1991
Highly Cited
1991
A set of oligonucleotide primers capable of initiating enzymatic amplification (polymerase chain reaction) on a phylogenetically… Expand
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Highly Cited
1989
Highly Cited
1989
With a standard set of primers directed toward conserved regions, we have used the polymerase chain reaction to amplify… Expand
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Highly Cited
1989
Highly Cited
1989
Using a set of synthetic oligonucleotides homologous to broadly conserved sequences in-vitro amplification via the polymerase… Expand
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