Diffuse mesangial sclerosis (disorder)
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BACKGROUND AND OBJECTIVES
To better define the clinical-pathologic spectrum and prognosis of monoclonal immunoglobulin deposition… Expand There remains a need for robust mouse models of diabetic nephropathy (DN) that mimic key features of advanced human DN. The… Expand BACKGROUND AND OBJECTIVES
Diffuse mesangial sclerosis (DMS) is a histologically distinct variant of nephrotic syndrome (NS) that… Expand Nephrotic syndrome, a malfunction of the kidney glomerular filter, leads to proteinuria, edema and, in steroid-resistant… Expand Congenital nephrotic syndrome (CNS) is clinically and genetically heterogeneous, with mutations in WT1, NPHS1 and NPHS2… Expand BACKGROUND
Mutations of NPHS2 are causative in familial autosomal-recessive (AR) and sporadic steroid-resistant nephrotic… Expand Glomerular disease is one of the most common causes of end-stage renal failure. Increasing evidence suggests that these… Expand Denys-Drash syndrome is a rare disorder of urogenital development characterized by the association of early onset glomerulopathy… Expand Constitutional mutations of the WT1 gene, encoding a zinc-finger transcription factor involved in renal and gonadal development… Expand The glomeruli of mice transgenic for bovine growth hormone (GH mice) were disproportionately enlarged as a function of either… Expand