Diffuse Scleroderma

Known as: Scleroderma, Sudden Onset, Diffuse Systemic Scleroses, dcSSc 
A variant of systemic scleroderma characterized by sclerosis of the skin, Raynaud phenomenon, and organ involvement, including pulmonary fibrosis… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1945-2018
05010015019452017

Papers overview

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Highly Cited
2014
Highly Cited
2014
IMPORTANCE High-dose immunosuppressive therapy and autologous hematopoietic stem cell transplantation (HSCT) have shown efficacy… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE To determine the safety of rituximab, to provide preliminary data regarding the potential efficacy of rituximab, and to… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Scleroderma is a clinically heterogeneous disease with a complex phenotype. The disease is characterized by vascular… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Systemic sclerosis (SSc) is a rare, heterogeneous disease, which affects different organs and therefore requires… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Systemic sclerosis (SSc) is a multisystem autoimmune disease, which is classified into a diffuse cutaneous (dcSSc) and… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Severe sepsis is common and frequently fatal, and community-acquired pneumonia (CAP) is the leading cause. Although… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVES To measure survival, haemodynamic function and functional class in patients with systemic sclerosis associated… (More)
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE To test the hypothesis that systemic sclerosis (SSc) patients taking high-dose D-penicillamine (D-Pen) would have… (More)
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Highly Cited
1997
Highly Cited
1997
OBJECTIVE To determine whether serum interleukin 4 (IL-4), IL-10, and IL-13 levels in patients with systemic sclerosis (SSc) are… (More)
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Highly Cited
1979
Highly Cited
1979
Skin biopsies of uniform location and surface area (7 mm diameter) were obtained from the extensor aspect of the forearm of 147… (More)
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