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Differentiation Inducer

Known as: Differentiating Agents, Differentiation Agents 
An agent that induces the differentiation or maturation of cells, specifically neoplastic cells, resulting in decreases in tumor growth and… 
National Institutes of Health

Papers overview

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Highly Cited
1997
Highly Cited
1997
Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors
Highly Cited
1996
Highly Cited
1996
Cell type-specific fusion cofactors determine human immunodeficiency virus type 1 tropism for T-cell lines versus primary macrophages
Work in this laboratory previously demonstrated that the tropism of different human immunodeficiency type 1 isolates for… 
Highly Cited
1996
Highly Cited
1996
Potentiation of myeloid differentiation by anti-inflammatory agents, by steroids and by retinoic acid involves a single intracellular target, probably an enzyme of the aldoketoreductase family.
Review
1995
Review
1995
Treatment of metastatic breast cancer: present and future prospects.
Patients with recurrent breast cancer can be divided into three categories: those with locoregional recurrence, those with… 
1993
1993
Regulation of UDP-GlcNAc:Gal beta 1-3GalNAc-R beta 1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in Chinese hamster ovary cells.
Highly Cited
1992
Highly Cited
1992
Modulation of P-glycoprotein phosphorylation and drug transport by sodium butyrate.
P-Glycoprotein (Pgp) expression in cell lines derived from tumors arising from cells which normally express Pgp can be increased… 
Highly Cited
1991
Highly Cited
1991
The high lysability by lak cells of colon‐carcinoma cells resistant to doxorubicin is associated with a high expression of ICAM‐1, LFA‐3, NCA and a less‐differentiated phenotype
A human colon‐carcinoma ceil subline resistant to doxorubicin (LoVo/Dx), previously shown to be more lysed than the… 
Highly Cited
1990
Highly Cited
1990
Differentiating agents facilitate infection of myeloid leukemia cell lines by monocytotropic HIV-1 strains.
Monocytotropic human immunodeficiency virus type 1 (HIV-1) isolates from patients with acquired immunodeficiency syndrome (AIDS… 
1990
1990
Karyotypic patterns in acute mixed lineage leukemia.
We performed cytogenetic and immunologic studies of blast cells from 13 children with acute mixed lineage leukemia (AMLL) to… 
Highly Cited
1989
Highly Cited
1989
Varied differentiation responses of human leukemias to bryostatin 1.
Bryostatin 1, a macrocyclic lactone isolated from a marine bryozoan, has significant antineoplastic activity against the murine… 
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