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Diacylglycerol Kinase Alpha

Known as: DAG Kinase Alpha, 80 kDa Diacylglycerol Kinase, Diacylglycerol Kinase, Alpha 
Diacylglycerol kinase alpha (735 aa, ~83 kDa) is encoded by the human DGKA gene. This protein is involved in the negative regulation of second… 
National Institutes of Health

Related topics

Related topics

12 relations
Calcium-Binding ProteinsDAG/PE-Binding DomainDGKA geneEnzyme Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Lck-Dependent Tyrosine Phosphorylation of Diacylglycerol Kinase α Regulates Its Membrane Association in T Cells1
TCR engagement triggers phospholipase Cγ1 activation through the Lck-ZAP70-linker of activated T cell adaptor protein pathway… 
Highly Cited
2005
Highly Cited
2005
Diacylglycerol Kinase α Regulates the Secretion of Lethal Exosomes Bearing Fas Ligand during Activation-induced Cell Death of T Lymphocytes*
Fas ligand (FasL) mediates both apoptotic and inflammatory responses in the immune system. FasL function critically depends on… 
2003
2003
Regulation of diacylglycerol kinase alpha by phosphoinositide 3-kinase lipid products.
Diacylglycerol kinase alpha (DAGK alpha), like all type I DAGKs, has calcium regulatory motifs that act as negative regulators of… 
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