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Dexverapamil

Known as: R verapamil, R-Verapamil 
The R-enantiomer of the calcium channel blocker verapamil. Dexverapamil competitively inhibits the multidrug resistance efflux pump P-glycoprotein… 
National Institutes of Health

Related topics

Related topics

2 relations
Verapamilcyclophosphamide/dexverapamil/doxorubicin/etoposide/prednisolone/vincristine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Dexverapamil as resistance modifier in acute myeloid leukaemia
In order to evaluate dexverapamil as a resistance modifier in acute myeloid leukaemia, we have added dexverapamil (4×300 mg/d… 
2006
2006
Dexverapamil to overcome epirubicin resistance in advanced breast cancer
Resistance to cytotoxic chemotherapy is a major problem in the management of patients with metastatic breast cancer. Various data… 
1999
1999
Multidrug resistance modulation in vivo: The effect of cyclosporin A alone or with dexverapamil on idarubicin pharmacokinetics in acute leukemia
AbstractObjective: To determine the effect of the coadministration of the multidrug resistance (MDR) modulators cyclosporin A… 
1999
1999
Alteration in Epirubicin Pharmacokinetics and Metabolism by Dexverapamil: Results from a Phase II Study in Patients with Metastatic Breast Cancer
Background: To study the effect of the resistance-modifying agent (RMA) dexverapamil on the pharmacokinetics and metabolism of… 
1997
1997
Os fármacos e a quiralidade: uma breve abordagem
The concepts of stereochemistry and chirality are introduced, and the ability to distinguish among the different receptors caused… 
1996
1996
Studies in phlebitis VIII: evaluations of pH solubilized intravenous dexverapamil formulations.
Injectable and infusion formulations of dexverapamil are evaluated for their potential to produce phlebitis. The evaluation… 
1996
1996
Clinical Reversal of Multidrug Resistance
Reversal of drug resistance offers the hope of increasing the efficacy of conventional chemotherapy. We tested dexverapamil as a… 
1996
1996
Rhodamine 123-efflux from hematopoietic subpopulations and leukaemic blast populations marked by PerCP-conjugated monoclonal antibodies.
1996
1996
P-glycoprotein-associated resistance to taxol and taxotere and its reversal by dexniguldipine-HCl, dexverapamil-HCl, or cyclosporin A.
A series of different human MDR (multidrug-resistant) cell lines including a HeLa-MDR1 transfectant which exhibit high… 
1995
1995
Self-association of dexverapamil in aqueous solution.
The pKa and intrinsic solubility of monomeric dexverapamil were determined from its pH-solubility profile to be 8.90 and 6.6 x 10… 
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