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Dexniguldipine Hydrochloride
Known as:
(S)-(+)-Watanidipine Hydrochloride
, Dexniguldipine.HCl
, ((-)-3-Methyl-5- 3-(4,4-diphenyl-l-piperidinyl)-propyl-l,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylate-hydrochloride)
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National Institutes of Health
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dexniguldipine
Papers overview
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2005
2005
Inhibition of protein-kinase-C — dependent cell proliferation of human lung cancer cell lines by the dihydropyridine dexniguldipine
H. Schuller
,
M. Orloff
,
G. Reznik
Journal of Cancer Research and Clinical Oncology
2005
Corpus ID: 39304647
The dihydropyridine, dexniguldipine hydrochloride (B859-35), has shown therapeutic activity in experimentally induced…
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2005
2005
Dexniguldipine hydrochloride, a protein-kinase-C-specific inhibitor, affects the cell cycle, differentiation, P-glycoprotein levels, and nuclear protein phosphorylation in friend erythroleukemia…
K. Patterson
,
B. Beckman
,
D. M. Klotz
,
C. Mallia
,
J. R. Jeter
Journal of Cancer Research and Clinical Oncology
2005
Corpus ID: 8905103
Dexniguldipine hydrochloride (DNIG) is a potent antineoplastic agent with well-documented anti-(protein kinase C) activity and an…
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1997
1997
The dihydropyridine dexniguldipine hydrochloride inhibits cleavage and religation reactions of eukaryotic DNA topoisomerase I.
T. Straub
,
C. Boesenberg
,
V. Gekeler
,
F. Boege
Biochemistry
1997
Corpus ID: 31954381
Dexniguldipine hydrochloride (B859-35, a dihydropyridine with antitumor and multidrug resistance-reverting activity) inhibits…
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1997
1997
DEXNIGULDIPINE HYDROCHLORIDE : MULTIDRUG RESISTANCE MODULATOR
C. Robinson
,
J. Castaǹer
1997
Corpus ID: 79153741
1996
1996
Modulation of multidrug resistance with dexniguldipine hydrochloride (B8509-035) in the CC531 rat colon carcinoma model
W. Vrie
,
A. Eggermont
,
+5 authors
G. Stoter
Journal of Cancer Research and Clinical Oncology
1996
Corpus ID: 22574074
The chemosensitizing potency of dexniguldipine hydrochloride (B8509-035) on epidoxorubicin was assessed in a multidrug-resistant…
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1996
1996
Dexniguldipine hydrochloride inhibits growth of human pancreatic adenocarcinoma cells and expression of protein kinase C isoforms alpha and zeta.
Y. Qin
,
Y. Tang
,
A. Schally
,
B. Beckman
International Journal of Oncology
1996
Corpus ID: 34152304
New therapeutic regimens are needed for the treatment of pancreatic cancer. In view of the importance of protein kinase C (PKC…
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1995
1995
Dexniguldipine hydrochloride inhibits growth of human ht-29 colon-carcinoma cells and expression of protein-kinase-C-delta and protein-kinase-C-zeta.
Y. Qin
,
Y. Tang
,
A. Schally
,
B. Beckman
International Journal of Oncology
1995
Corpus ID: 10051785
Previous studies have implicated protein kinase C (PKC) in colon carcinogenesis, but a clear understanding of the role of PKC in…
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