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Destrin

Known as: ADF Protein (Actin Depolymerizing Factor), Depolymerizing Factor, Actin, Actin Depolymerizing Factor 
A member of the actin depolymerizing factors. Its depolymerizing activity is independent of HYDROGEN-ION CONCENTRATION.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Dendritic spines undergo actin-based growth and shrinkage during synaptic plasticity, in which the actin depolymerizing factor… Expand
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Highly Cited
2009
Highly Cited
2009
Dynamic actin remodelling processes at the leading edge of migrating tumour cells are concerted events controlled by a fine-tuned… Expand
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Review
2004
Review
2004
Actin and microtubules are major cytoskeletal elements of most cells including neurons. In order for a cell to move and change… Expand
Highly Cited
2003
Highly Cited
2003
The dendritic spine is an important site of neuronal plasticity and contains extremely high levels of cytoskeletal actin. However… Expand
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Highly Cited
2000
Highly Cited
2000
Growth cone motility is regulated by changes in actin dynamics. Actin depolymerizing factor (ADF) is an important regulator of… Expand
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Review
2000
Review
2000
The most important discovery in the field is that the Arp2/3 complex nucleates assembly of actin filaments with free barbed ends… Expand
Highly Cited
1999
Highly Cited
1999
Actin polymerization is essential for cell locomotion and is thought to generate the force responsible for cellular protrusions… Expand
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Highly Cited
1997
Highly Cited
1997
Actin-binding proteins of the actin depolymerizing factor (ADF)/cofilin family are thought to control actin-based motile… Expand
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Highly Cited
1995
Highly Cited
1995
Actin depolymerizing factor (ADF) occurs naturally in two forms, one of which contains a phosphorylated Ser and does not bind G… Expand
Highly Cited
1990
Highly Cited
1990
Cofilin is a widely distributed actin-modulating protein that has the ability to bind along the side of F-actin and to… Expand
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