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Dendritic spines undergo actin-based growth and shrinkage during synaptic plasticity, in which the actin depolymerizing factor… Expand Dynamic actin remodelling processes at the leading edge of migrating tumour cells are concerted events controlled by a fine-tuned… Expand Actin and microtubules are major cytoskeletal elements of most cells including neurons. In order for a cell to move and change… Expand The dendritic spine is an important site of neuronal plasticity and contains extremely high levels of cytoskeletal actin. However… Expand Growth cone motility is regulated by changes in actin dynamics. Actin depolymerizing factor (ADF) is an important regulator of… Expand The most important discovery in the field is that the Arp2/3 complex nucleates assembly of actin filaments with free barbed ends… Expand Actin polymerization is essential for cell locomotion and is thought to generate the force responsible for cellular protrusions… Expand Actin-binding proteins of the actin depolymerizing factor (ADF)/cofilin family are thought to control actin-based motile… Expand Actin depolymerizing factor (ADF) occurs naturally in two forms, one of which contains a phosphorylated Ser and does not bind G… Expand Cofilin is a widely distributed actin-modulating protein that has the ability to bind along the side of F-actin and to… Expand