Actin Depolymerizing Factors

Known as: ADF Proteins (Actin Depolymerizing Factors), Actin Depolymerizing Proteins, Cofilins 
A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2018
051019852018

Papers overview

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Highly Cited
2011
Highly Cited
2011
Intracellular and extracellular mechanical forces affect the structure and dynamics of the actin cytoskeleton. However, the… (More)
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2010
2010
The actin depolymerizing factors (ADFs) play important roles in several cellular processes that require cytoskeletal… (More)
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2010
2010
Toxoplasma gondii is a protozoan parasite belonging to the phylum Apicomplexa. Parasites in this phylum utilize a unique process… (More)
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Highly Cited
2006
Highly Cited
2006
ADF/cofilins are key regulators of actin dynamics during cellular motility, yet their precise role and mechanism of action are… (More)
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Highly Cited
2005
Highly Cited
2005
Actin-depolymerizing factor (ADF)/cofilins are small actin-binding proteins found in all eukaryotes. In vitro, ADF/cofilins… (More)
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Highly Cited
2005
Highly Cited
2005
Cofilin/ADF proteins are a ubiquitously expressed family of F-actin depolymerizing factors found in eukaryotic cells including… (More)
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Highly Cited
2003
Highly Cited
2003
Pollen tube elongation is a rapid tip growth process that is driven by a dynamic actin cytoskeleton. A ubiquitous family of actin… (More)
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Highly Cited
2002
Highly Cited
2002
Actin-depolymerizing factor (ADF)/cofilins are essential regulators of actin filament turnover. Several ADF/cofilin isoforms are… (More)
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Highly Cited
1997
Highly Cited
1997
Cofilin stimulates actin filament turnover in vivo. The phenotypes of twenty yeast cofilin mutants generated by systematic… (More)
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Highly Cited
1996
Highly Cited
1996
Two cDNAs, isolated from a Xenopus laevis embryonic library, encode proteins of 168 amino acids, both of which are 77% identical… (More)
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