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Actin Depolymerizing Factors

Known as: ADF Proteins (Actin Depolymerizing Factors), Actin Depolymerizing Proteins, Cofilins 
A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
In vitro, actin filament tension correlates with the binding and apparent activity of the filament-severing protein cofilin… Expand
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Highly Cited
2010
Highly Cited
2010
Crawling locomotion of eukaryotic cells is achieved by a process dependent on the actin cytoskeleton: protrusion of the leading… Expand
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Highly Cited
2006
Highly Cited
2006
ADF/cofilins are key regulators of actin dynamics during cellular motility, yet their precise role and mechanism of action are… Expand
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Highly Cited
2005
Highly Cited
2005
Actin-depolymerizing factor (ADF)/cofilins are small actin-binding proteins found in all eukaryotes. In vitro, ADF/cofilins… Expand
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Highly Cited
2005
Highly Cited
2005
Cofilin/ADF proteins are a ubiquitously expressed family of F-actin depolymerizing factors found in eukaryotic cells including… Expand
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Highly Cited
2002
Highly Cited
2002
The ADF (actin-depolymerizing factor)/cofilin family is a stimulus-responsive mediator of actin dynamics. In contrast to the… Expand
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Review
2002
Review
2002
SummaryThe ADF/cofilins are a family of actin-binding proteins expressed in all eukaryotic cells so far examined. Members of this… Expand
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Review
2002
Review
2002
ADF/cofilins are key regulators of actin dynamics in normal cells. Recent findings suggest that, under cellular stress, the wild… Expand
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Highly Cited
2002
Highly Cited
2002
Actin-depolymerizing factor (ADF)/cofilins are essential regulators of actin filament turnover. Several ADF/cofilin isoforms are… Expand
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Review
1999
Review
1999
  • James R. Bamburg
  • Annual review of cell and developmental biology
  • 1999
  • Corpus ID: 36439593
Ubiquitous among eukaryotes, the ADF/cofilins are essential proteins responsible for the high turnover rates of actin filaments… Expand
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