FAQ

Des-Gamma Carboxyprothrombin

Known as: DCP, PIVKA-II, Protein Induced by Vitamin K Absence/Antagonist-II 
Des-gamma carboxyprothrombin (622 aa, ~70 kDa) is encoded by the human F2 gene. This protein is involved in blood coagulation. This form of… (More)

Topic mentions per year

Topic mentions per year

1971-2018
0204019712018

Related topics

Related topics

12 relations
Blood coagulationEnzyme GeneF2 geneHydrolase Gene
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Des-Gamma Carboxyprothrombin
Hydrolysis
Liver carcinoma
Proteolysis
F2 gene
Blood coagulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Effect of vitamin K2 supplementation on functional vitamin K deficiency in hemodialysis patients: a randomized trial.
BACKGROUND Vascular calcification is a predictor of cardiovascular morbidity and mortality. Hemodialysis patients experience… (More)
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2011
2011
Circulating nonphosphorylated carboxylated matrix gla protein predicts survival in ESRD.
The mechanisms for vascular calcification and its associated cardiovascular mortality in patients with ESRD are not completely… (More)
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2010
2010
Vitamins K and D status in stages 3-5 chronic kidney disease.
BACKGROUND AND OBJECTIVES Vitamin K, vitamin K-dependent proteins, and vitamin D may be involved in the regulation of… (More)
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Highly Cited
2008
Highly Cited
2008
Serum proteomics and biomarkers in hepatocellular carcinoma and chronic liver disease.
PURPOSE Proteomic profiling using surface enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF MS… (More)
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Highly Cited
2006
Highly Cited
2006
VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection).
BACKGROUND The haplotypes in the gene vitamin K epoxide reductase complex subunit 1 (VKORC1) have been found to affect warfarin… (More)
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Highly Cited
2003
Highly Cited
2003
Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker.
With the global pandemic of hepatitis B and C infections, the incidence of Hepatocellular carcinoma (HCC) is rapidly increasing… (More)
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Highly Cited
2002
Highly Cited
2002
Occurrence and microbial degradation of phthalate esters in Taiwan river sediments.
Concentrations and microbial degradation rates were measured for eight phthalate esters (PAEs) found in 14 surface water and six… (More)
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2000
2000
Prospective analysis of risk factors for early intrahepatic recurrence of hepatocellular carcinoma following ethanol injection.
BACKGROUND/AIM Time-dependent intrahepatic recurrence of hepatocellular carcinoma is frequent after different treatment… (More)
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1999
1999
Process of carboxylation of glutamic acid residues in the gla domain of human des-gamma-carboxyprothrombin.
In the absence of vitamin K (VK) or in the presence of VK antagonists, hepatic VK-dependent carboxylase activity is inhibited and… (More)
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1996
1996
Comparison of biochemical indexes for assessing vitamin K nutritional status in a healthy adult population.
Biochemical indexes for assessing vitamin K nutritional status were evaluated in 263 healthy subjects (127 males, 136 females… (More)
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