Dependence

Known as: dependence on 
The psychological or physiological need to take a substance in oder to experience its effects or to avoid the effects of its absence.

Topic mentions per year

Topic mentions per year

1935-2018
0500100019352017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Many breast cancers exhibit a degree of dependence on estrogen for tumor growth. Although several therapies have been developed… (More)
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Highly Cited
2008
Highly Cited
2008
whose conditions continued to progress despite antiretroviral therapy. The subjects with a dominant IL-2 response had very low… (More)
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Highly Cited
2007
Highly Cited
2007
Today nanosciences are experiencing massive investment worldwide although research on toxicological aspects of these nano-sized… (More)
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Highly Cited
2005
Highly Cited
2005
We introduce the Bayesian skyline plot, a new method for estimating past population dynamics through time from a sample of… (More)
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Highly Cited
2004
Highly Cited
2004
Peripheral autoantigen binding B cells are poorly competitive with naive B cells for survival and undergo rapid cell death… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND In order to develop informed approaches to prevention and treatment of illicit psychoactive substance use, abuse, and… (More)
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Highly Cited
1998
Highly Cited
1998
Alcohol dependence is a leading cause of morbidity and premature death. Several lines of evidence suggest a substantial genetic… (More)
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Highly Cited
1997
Highly Cited
1997
One of the most common microsatellites in eukaryotes consists of tandem arrays [usually 15-50 base pairs (bp) in length] of the… (More)
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Highly Cited
1986
Highly Cited
1986
We studied the in vivo recombination between homologous DNA sequences cloned in phage lambda and a pBR322-derived plasmid by… (More)
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Highly Cited
1984
Highly Cited
1984
In glucocorticoid-treated rat thymocytes and the murine lymphoid cell lines L5178 and S49 the morphology of apoptosis is… (More)
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