Deficiency of glycerol kinase

Known as: HYPERGLYCEROLEMIA, GKD, Glycerol kinase deficiency 
A rare, X-linked recessive genetic disorder of glycerol metabolism caused by mutations or deletion in the GK gene. It results in deficiency of the… (More)
National Institutes of Health

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Frontal bossingGK geneGK wt AlleleHypoglycemia
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Broader (1)

Glycerol Kinase

Papers overview

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Review
2010
Review
2010
Hypolipidemic, antioxidant, and antiinflammatory activities of microalgae Spirulina.
Spirulina is free-floating filamentous microalgae growing in alkaline water bodies. With its high nutritional value, Spirulina… (More)
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2009
2009
Transcriptomic and network component analysis of glycerol kinase in skeletal muscle using a mouse model of glycerol kinase deficiency.
Glycerol kinase (GK) is at the interface of fat and carbohydrate metabolism and has been linked to obesity and type 2 diabetes… (More)
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2007
2007
Glycerol kinase deficiency alters expression of genes involved in lipid metabolism, carbohydrate metabolism, and insulin signaling
Glycerol kinase (GK) is at the interface of fat and carbohydrate metabolism and has been implicated in insulin resistance and… (More)
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2002
2002
Lethal hypoglycemic ketosis and glyceroluria in mice lacking both the mitochondrial and the cytosolic glycerol phosphate dehydrogenases.
The activities of either the mitochondrial or cytosolic glycerol phosphate dehydrogenase (mGPD, cGPD) plus that of glycerol… (More)
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2001
2001
Glycerol kinase deficiency: Evidence for complexity in a single gene disorder
Glycerol kinase deficiency (GKD) occurs as part of an Xp21 contiguous gene syndrome or as isolated GKD. The isolated form can be… (More)
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1997
1997
Electrophysiological changes that accompany reactive gliosis in vitro.
An in vitro injury model was used to examine the electrophysiological changes that accompany reactive gliosis. Mechanical… (More)
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1997
1997
X-linked glycerol kinase deficiency in the mouse leads to growth retardation, altered fat metabolism, autonomous glucocorticoid secretion and neonatal death.
Glycerol kinase is an X chromosome-encoded enzyme involved in the metabolism of endogenous and dietary glycerolipids. The… (More)
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Highly Cited
1994
Highly Cited
1994
Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism
ADRENAL hypoplasia congenita (AHC) is an X-linked disorder characterized by primary adrenal insufficiency1,2. Hypogonadotropic… (More)
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1987
1987
Congenital adrenal hypoplasia, myopathy, and glycerol kinase deficiency: molecular genetic evidence for deletions.
Glycerol kinase deficiency (GKD) is an X-linked recessive trait that occurs in association with congenital adrenal hypoplasia (AH… (More)
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1983
1983
Human glycerol kinase deficiency: an inborn error of compartmental metabolism.
Twelve individuals have been described with glycerol kinase deficiency. Five of these individuals are adults who were noted… (More)
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