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Deep Sequencing

Known as: Deep Sequencings, Sequencing, Deep, Sequencings, Deep 
Techniques of nucleotide sequence analysis that increase the scale of operations enabling an increase in the depth of coverage (number of copies) to… Expand
National Institutes of Health

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High-Throughput Nucleotide Sequencing

Papers overview

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Review
2019
Review
2019
Transcriptome of Extracellular Vesicles: State-of-the-Art
Exosomes and microvesicles are two major categories of extracellular vesicles (EVs) released by almost all cell types and are… Expand
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Highly Cited
2015
Highly Cited
2015
A global reference for human genetic variation
The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole… Expand
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Highly Cited
2014
Highly Cited
2014
miRBase: annotating high confidence microRNAs using deep sequencing data
We describe an update of the miRBase database (http://www.mirbase.org/), the primary microRNA sequence repository. The latest… Expand
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Highly Cited
2013
Highly Cited
2013
Characterization of human plasma-derived exosomal RNAs by deep sequencing
BackgroundExosomes, endosome-derived membrane microvesicles, contain specific RNA transcripts that are thought to be involved in… Expand
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Highly Cited
2012
Highly Cited
2012
Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes
A Deep Look Into Our Genes Recent debates have focused on the degree of genetic variation and its impact upon health at the… Expand
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Highly Cited
2012
Highly Cited
2012
Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA
Sizable genomic regions were screened and low-frequency mutations were identified in circulating DNA of cancer patients using… Expand
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Highly Cited
2012
Highly Cited
2012
The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments
Recent studies highlight the importance of translational control in determining protein abundance, underscoring the value of… Expand
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Highly Cited
2011
Highly Cited
2011
Deep sequencing reveals 50 novel genes for recessive cognitive disorders
Common diseases are often complex because they are genetically heterogeneous, with many different genetic defects giving rise to… Expand
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Highly Cited
2008
Highly Cited
2008
Discovering microRNAs from deep sequencing data using miRDeep
The capacity of highly parallel sequencing technologies to detect small RNAs at unprecedented depth suggests their value in… Expand
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Highly Cited
2008
Highly Cited
2008
Deep sequencing-based expression analysis shows major advances in robustness, resolution and inter-lab portability over five microarray platforms
The hippocampal expression profiles of wild-type mice and mice transgenic for δC-doublecortin-like kinase were compared with… Expand
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