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Debrisoquine sulfate

Known as: DEBRISOQUIN SULFATE 
 
National Institutes of Health

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Debrisoquin

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1988
1988
The degree of PCB chlorination determines whether the rise in urinary homovanillic acid production in rats is peripheral or central in origin.
Commercial mixtures of polychlorinated biphenyls (PCBs, Aroclor 1016, 1254, and 1260) differing in their degree of chlorination… Expand
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1986
1986
Increased catecholamine output in the hypertensive fawn-hooded rat.
The total 24 hour urinary outputs of the catecholamines norepinephrine (NE), epinephrine (E), dopamine (DA) and the DA metabolite… Expand
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1984
1984
Studies on the central or peripheral origin of free and sulfated 3,4-dihydroxyphenylacetic acid in rat plasma.
The concentrations of free and sulfated 3,4-dihydroxyphenylacetic acid (DOPAC) were measured in rat plasma to investigate their… Expand
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1982
1982
Brain catecholamine metabolites and behavior in morphine withdrawal.
Morphine withdrawal behavior, brain and plasma catecholamine metabolites, and brain beta-noradrenergic receptor binding were… Expand
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1980
1980
Ethnic difference in drug metabolism: debrisoquine 4-hydroxylation in Caucasians and Orientals.
The extent to which debrisoquine (D) is metabolized to 4-hydroxydebrisoquine (4OHD) was found to be influenced by the ethnic… Expand
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1980
1980
Catecholamine metabolites in human plasma as indices of brain function: effects of debrisoquin.
Abstract Metabolites of catecholamine neurotransmitters in plasma are, potentially, an easily available indicator of brain… Expand
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1975
1975
Metabolism of debrisoquine sulfate. Identification of some urinary metabolites in rat and man.
A high proportion of an oral dose of 14C-debrisoquine sulfate is excreted in the urine by rat and man. The urinary radioactivity… Expand
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1969
1969
The interactions of local guanethidine and sympathomimetic amines in the human eye.
The responses of the human eye to the intraocular administration of the adrenergic neurone blocking drugs guanethidine sulfate… Expand
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1968
1968
Clinical evaluation of debrisoquin in the treatment of hypertension.
Sixty-three hypertensive patients were treated with debrisoquin sulfate, a new sympathetic blocking drug, for periods of 6 to 33… Expand
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1966
1966
Cardiac and renal hemodynamic effects of debrisoquin sulfate in hypertensive patients.
 
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