Debrisoquine sulfate

Debrisoquine (D), an antihypertensive drug metabolized to 4-hydroxydebrisoquine (4-OHD) by CYP2D6, is commonly used as an in vivo… Expand

Central dopaminergic (DA) function in children was assessed by monitoring plasma-free homovanillic acid (pHVA) levels after brief… Expand

The total 24 hour urinary outputs of the catecholamines norepinephrine (NE), epinephrine (E), dopamine (DA) and the DA metabolite… Expand

Morphine withdrawal behavior, brain and plasma catecholamine metabolites, and brain beta-noradrenergic receptor binding were… Expand

Abstract Metabolites of catecholamine neurotransmitters in plasma are, potentially, an easily available indicator of brain… Expand

The extent to which debrisoquine (D) is metabolized to 4-hydroxydebrisoquine (4OHD) was found to be influenced by the ethnic… Expand

A high proportion of an oral dose of 14C-debrisoquine sulfate is excreted in the urine by rat and man. The urinary radioactivity… Expand

The responses of the human eye to the intraocular administration of the adrenergic neurone blocking drugs guanethidine sulfate… Expand

Sixty-three hypertensive patients were treated with debrisoquin sulfate, a new sympathetic blocking drug, for periods of 6 to 33… Expand

Debrisoquin sulfate is a moderately potent antihypertensive agent with a predominant orthostatic antihypertensive action. The… Expand