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Debrisoquine sulfate

Known as: DEBRISOQUIN SULFATE 
National Institutes of Health

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Debrisoquin

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Papers overview

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2000
2000
Enantioselectivity of debrisoquine 4-hydroxylation in Brazilian Caucasian hypertensive patients phenotyped as extensive metabolizers.
1988
1988
The degree of PCB chlorination determines whether the rise in urinary homovanillic acid production in rats is peripheral or central in origin.
1986
1986
Increased catecholamine output in the hypertensive fawn-hooded rat.
The total 24 hour urinary outputs of the catecholamines norepinephrine (NE), epinephrine (E), dopamine (DA) and the DA metabolite… 
1986
1986
Brief debrisoquin administration to assess central dopaminergic function in children.
1982
1982
Brain catecholamine metabolites and behavior in morphine withdrawal.
Highly Cited
1980
Highly Cited
1980
Catecholamine metabolites in human plasma as indices of brain function: effects of debrisoquin.
Highly Cited
1980
Highly Cited
1980
Ethnic difference in drug metabolism: debrisoquine 4-hydroxylation in Caucasians and Orientals.
The extent to which debrisoquine (D) is metabolized to 4-hydroxydebrisoquine (4OHD) was found to be influenced by the ethnic… 
1975
1975
Metabolism of debrisoquine sulfate. Identification of some urinary metabolites in rat and man.
A high proportion of an oral dose of 14C-debrisoquine sulfate is excreted in the urine by rat and man. The urinary radioactivity… 
1968
1968
Clinical evaluation of debrisoquin in the treatment of hypertension.
Sixty-three hypertensive patients were treated with debrisoquin sulfate, a new sympathetic blocking drug, for periods of 6 to 33… 
1966
1966
Cardiac and renal hemodynamic effects of debrisoquin sulfate in hypertensive patients
Debrisoquin sulfate is a moderately potent antihypertensive agent with a predominant orthostatic antihypertensive action. The… 
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