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Daporinad

Known as: (2E)-N-(4-(1-Benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)prop-2-enamide 
A small molecule with potential antineoplastic and antiangiogenic activities. Daporinad binds to and inhibits nicotinamide phosphoribosyltransferase… Expand
National Institutes of Health

Papers overview

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2018
2018
FK866 (Daporinad or APO866) is a specific inhibitor of NAMPT (nicotinamide phosphoribosyltransferase), a rate limiting enzyme… Expand
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2018
2018
Despite the availability of the effective targeted therapies in lung cancer, such as EGFR tyrosine kinase inhibitors (TKIs), drug… Expand
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2017
2017
PARP inhibitors (PARPi) have exhibited clinical success in inherited breast cancers with mutations in homologous recombination… Expand
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2017
2017
Lung cancer is the leading cause of cancer death in western countries. It is highly resistant to the conventional therapy… Expand
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2015
2015
Pre-B cell colony-enhancing factor (PBEF) is a highly conserved pleiotropic protein reported to be an alternate ligand for the… Expand
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