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DU 145

A cell line made from human prostate cancer cells that is used in the laboratory to study the way prostate cancer cells grow.
National Institutes of Health

Papers overview

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2005
2005
Predicting Aggregation Kinetics of DU 145 Prostate Cancer Cells in Liquid-Overlay Culture
The predictive capacity of a novel population-balance model to simulate aggregation kinetics of attachment-dependent cells at the… 
2003
2003
NOX 5 NAD ( P ) H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells
Sukhdev S. Brar,1 Zachary Corbin,1 Thomas P. Kennedy,1 Richelle Hemendinger,2 Lisa Thornton,3 Bettina Bommarius,4 Rebecca S… 
2002
2002
The environmental toxin 2,3,7,8-tetrachlorodibenzo-p-dioxin induces cytochrome P450 activity in high passage PC 3 and DU 145 human prostate cancer cell lines.
The study was conducted to investigate whether 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces cytochrome P450 (CYP) 1A1 and… 
2001
2001
Comparison of the malignant phenotype and genotype of the human androgen-independent cell line DU 145 and a subline derived from metastasis after orthotopic implantation in nude mice.
2000
2000
Impairment of erbB 1 receptor and fluid-phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma DU 145 cells
Recently, we observed that epidermal growth factor receptor (EGFR or erbB1) endocytosis and associated mitogenic signaling occur… 
Highly Cited
1999
Highly Cited
1999
Liarozole Acts Synergistically with 1α,25-Dihydroxyvitamin D3 to Inhibit Growth of DU 145 Human Prostate Cancer Cells by Blocking 24-Hydroxylase Activity.
1α,25-Dihydroxyvitamin D3[ 1,25-(OH)2D3] inhibits the proliferation of many cancer cells in culture, but not the aggressive human… 
1999
1999
Oncostatin M (OM) promotes the growth of DU 145 human prostate cancer cells, but not PC-3 or LNCaP, through the signaling of the OM specific receptor.
BACKGROUND Oncostain M (OM) is a member of the interleukin-6 (IL-6) cytokine family and all members utilize gp130 as a common… 
Highly Cited
1998
Highly Cited
1998
Growth‐inhibitory effects of luteinizing hormone‐releasing hormone (LHRH) agonists on xenografts of the DU 145 human androgen‐independent prostate cancer cell line in nude mice
Experiments have been performed to clarify whether LHRH agonists might decrease growth of hormone‐unresponsive prostate cancer in… 
1995
1995
Differential expression of uPA in an aggressive (DU 145) and a nonaggressive (1013L) human prostate cancer xenograft
Prostate cancer has a slow growing noninvasive phase, but, in general, is invasive on diagnosis. An initial step in the invasion… 
1993
1993
Growth of prostatic cancer cells, DU 145, as multicellular spheroids and effects of estramustine.
The human prostatic carcinoma cell line DU 145 was grown as multicellular spheroids in vitro. The volume doubling time during the… 
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