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DSP 4

Known as: DSP-4, DSP4, az-DSP 4 
 
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
Locus ceruleus (LC) degeneration and loss of cortical noradrenergic innervation occur early in Alzheimer’s disease (AD). Although… Expand
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Highly Cited
2006
Highly Cited
2006
Starch is the ultimate storage molecule formed in the photosynthetic fixation of carbon dioxide by chloroplasts. Starch… Expand
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Highly Cited
2002
Highly Cited
2002
Degeneration of locus ceruleus (LC) neurons and reduced levels of norepinephrine (NE) in LC projection areas are well known… Expand
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Highly Cited
1994
Highly Cited
1994
  • K. Davis
  • Neuropsychopharmacology
  • 1994
  • Corpus ID: 5977401
Data generated to date by a number of large studies (Eagger et al, Davis et al, Farlow et al, and Murphy et al) indicate that… Expand
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Highly Cited
1989
Highly Cited
1989
N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) is a potent and highly selective neurotoxin which induces degeneration of… Expand
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Highly Cited
1987
Highly Cited
1987
In Alzheimer's disease (AD), pathological changes are found in the basal forebrain cholinergic system (BFCS), serotonergic raphe… Expand
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Highly Cited
1983
Highly Cited
1983
A peripheral injection of DSP-4 [N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine] produced a marked, selective, and lasting… Expand
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Highly Cited
1982
Highly Cited
1982
The effect of the noradrenaline neurotoxin DSP4 on the postnatal development of central noradrenergic neurons in the rat has been… Expand
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Highly Cited
1981
Highly Cited
1981
The effect of N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP4) on monoamine neurons was studied in mice and rats. In mice DSP4… Expand
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Highly Cited
1980
Highly Cited
1980
The pharmacological actions of the compound N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride (DSP-4) are compatible… Expand
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