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DRAM1 gene

Known as: FLJ11259, DRAM1, DNA damage regulated autophagy modulator 1 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
DRAM1 (DNA damage-regulated autophagy modulator 1) is a TP53 target gene that modulates autophagy and apoptosis. We previously… Expand
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Highly Cited
2014
Highly Cited
2014
Autophagy is an important defense mechanism against mycobacteria, the causative agents of tuberculosis. The molecular mechanisms… Expand
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Highly Cited
2013
Highly Cited
2013
The aggressiveness of glioblastoma multiforme (GBM) is defined by local invasion and resistance to therapy. Within established… Expand
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Highly Cited
2013
Highly Cited
2013
Systemic lupus erythematosus (SLE) is a prototype autoimmune disease with a strong genetic involvement and ethnic differences… Expand
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Review
2010
Review
2010
p53 and JNK are two apoptosis-regulatory factors frequently deregulated in cancer cells and also involved in the modulation of… Expand
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Highly Cited
2009
Highly Cited
2009
The oncosuppressor protein p53 regulates autophagy in a dual fashion. The pool of cytoplasmic p53 protein represses autophagy in… Expand
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Review
2007
Review
2007
It is clear that changes in autophagy and autophagy regulators occur during tumor development and that this can have profound… Expand
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Highly Cited
2007
Highly Cited
2007
Evading programmed cell death is a common event in tumour development. The p53 family member, p73, is a potent inducer of death… Expand
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2007
2007
The tumor suppressor p53 regulates diverse biological processes primarily via activation of downstream target genes. Even though… Expand
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Highly Cited
2006
Highly Cited
2006
Inactivation of cell death is a major step in tumor development, and p53, a tumor suppressor frequently mutated in cancer, is a… Expand
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